Matches in SemOpenAlex for { <https://semopenalex.org/work/W2419468057> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2419468057 endingPage "182" @default.
- W2419468057 startingPage "177" @default.
- W2419468057 abstract "Focal cerebral ischaemia was induced in seven anaesthetized monkeys by unilateral middle cerebral artery (MCA) occlusion. Local cerebral blood flow (CBF) and computer mapped EEG (CME) changes were then studied as blood volume and cardiac output (CO) were varied. CO was increased by colloidal volume expansion and decreased by exsanguination. Local CBF fell to 24 ± 9% of control values in ischaemic areas following MCA occlusion and increased to 43 ± 19% of control values (p < 0.01) when CO was increased by 130 ± 70% with colloid infusion. Local CBF to nonischaemic regions was not altered significantly by blood volume expansion. Exsanguination led to return of CO to control levels and was associated with reduction of local CBF in ischaemic regions to 24 ± 12% of control values (p < 0.05).CME showed bifrontal or ipsilateral slow wave foci (delta) following MCA occlusion. Blood volume expansion brought about a marked reduction of this slow wave activity and exsanguination led to recurrence of the slow wave foci.This data demonstrated that colloidal blood volume expansion induced an increase in local CBF and improved neuroelectric status of ischaemic brain following MCA occlusion. It was also shown that a reduction of blood volume and cardiac output resulted in a reduction in local CBF and a worsening of neuroelectric status in ischaemic areas. This study supports the contention that blood volume and cardiac output maintenance is extremely important in the management of acute ischaemic stroke." @default.
- W2419468057 created "2016-06-24" @default.
- W2419468057 creator A5011450958 @default.
- W2419468057 creator A5031254269 @default.
- W2419468057 creator A5033793335 @default.
- W2419468057 creator A5044503012 @default.
- W2419468057 creator A5085998566 @default.
- W2419468057 date "1986-09-01" @default.
- W2419468057 modified "2023-09-25" @default.
- W2419468057 title "Blood volume expansion with hetastarch in acute ischaemic stroke: the effects on local cerebral blood flow and computer mapped EEG" @default.
- W2419468057 cites W1483296618 @default.
- W2419468057 cites W193107804 @default.
- W2419468057 cites W1978181946 @default.
- W2419468057 cites W1978412440 @default.
- W2419468057 cites W1991112938 @default.
- W2419468057 cites W2000228848 @default.
- W2419468057 cites W2002798001 @default.
- W2419468057 cites W2004169263 @default.
- W2419468057 cites W2004531802 @default.
- W2419468057 cites W2014786395 @default.
- W2419468057 cites W2022268454 @default.
- W2419468057 cites W2038475233 @default.
- W2419468057 cites W2042479445 @default.
- W2419468057 cites W2050847320 @default.
- W2419468057 cites W2058433958 @default.
- W2419468057 cites W2064824302 @default.
- W2419468057 cites W2080541228 @default.
- W2419468057 cites W2082342695 @default.
- W2419468057 cites W2125445260 @default.
- W2419468057 cites W2156391364 @default.
- W2419468057 cites W2411004889 @default.
- W2419468057 cites W2411620061 @default.
- W2419468057 cites W2416759009 @default.
- W2419468057 cites W2439047228 @default.
- W2419468057 cites W2474777318 @default.
- W2419468057 cites W1495680570 @default.
- W2419468057 cites W52674478 @default.
- W2419468057 doi "https://doi.org/10.1080/01616412.1986.11739751" @default.
- W2419468057 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2430227" @default.
- W2419468057 hasPublicationYear "1986" @default.
- W2419468057 type Work @default.
- W2419468057 sameAs 2419468057 @default.
- W2419468057 citedByCount "13" @default.
- W2419468057 countsByYear W24194680572012 @default.
- W2419468057 crossrefType "journal-article" @default.
- W2419468057 hasAuthorship W2419468057A5011450958 @default.
- W2419468057 hasAuthorship W2419468057A5031254269 @default.
- W2419468057 hasAuthorship W2419468057A5033793335 @default.
- W2419468057 hasAuthorship W2419468057A5044503012 @default.
- W2419468057 hasAuthorship W2419468057A5085998566 @default.
- W2419468057 hasConcept C157767197 @default.
- W2419468057 hasConcept C158846371 @default.
- W2419468057 hasConcept C164705383 @default.
- W2419468057 hasConcept C2775841333 @default.
- W2419468057 hasConcept C2776268601 @default.
- W2419468057 hasConcept C2778198053 @default.
- W2419468057 hasConcept C37557685 @default.
- W2419468057 hasConcept C42219234 @default.
- W2419468057 hasConcept C541997718 @default.
- W2419468057 hasConcept C71924100 @default.
- W2419468057 hasConcept C78085059 @default.
- W2419468057 hasConcept C80461066 @default.
- W2419468057 hasConceptScore W2419468057C157767197 @default.
- W2419468057 hasConceptScore W2419468057C158846371 @default.
- W2419468057 hasConceptScore W2419468057C164705383 @default.
- W2419468057 hasConceptScore W2419468057C2775841333 @default.
- W2419468057 hasConceptScore W2419468057C2776268601 @default.
- W2419468057 hasConceptScore W2419468057C2778198053 @default.
- W2419468057 hasConceptScore W2419468057C37557685 @default.
- W2419468057 hasConceptScore W2419468057C42219234 @default.
- W2419468057 hasConceptScore W2419468057C541997718 @default.
- W2419468057 hasConceptScore W2419468057C71924100 @default.
- W2419468057 hasConceptScore W2419468057C78085059 @default.
- W2419468057 hasConceptScore W2419468057C80461066 @default.
- W2419468057 hasIssue "3" @default.
- W2419468057 hasLocation W24194680571 @default.
- W2419468057 hasLocation W24194680572 @default.
- W2419468057 hasOpenAccess W2419468057 @default.
- W2419468057 hasPrimaryLocation W24194680571 @default.
- W2419468057 hasRelatedWork W191017088 @default.
- W2419468057 hasRelatedWork W1978136238 @default.
- W2419468057 hasRelatedWork W2014280799 @default.
- W2419468057 hasRelatedWork W2039404300 @default.
- W2419468057 hasRelatedWork W2059537885 @default.
- W2419468057 hasRelatedWork W2086504482 @default.
- W2419468057 hasRelatedWork W2123894485 @default.
- W2419468057 hasRelatedWork W2441321210 @default.
- W2419468057 hasRelatedWork W2460634951 @default.
- W2419468057 hasRelatedWork W3143204617 @default.
- W2419468057 hasVolume "8" @default.
- W2419468057 isParatext "false" @default.
- W2419468057 isRetracted "false" @default.
- W2419468057 magId "2419468057" @default.
- W2419468057 workType "article" @default.