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- W2419515402 abstract "We attempt to assess the appropriate sequence of bronchial biopsy and bronchial brushing for a better cytological diagnostic yield. The fiberoptic bronchoscopy was conducted in patients with negative sputum cytology to investigate endobronchial lesions by means of pre- and post-biopsy brushing cytology. The cytological results were compared with those of biopsies. Thirty-six patients with endobronchial lesion were found by bronchoscopy, and 29 had confirmed diagnosis after follow-up. The diagnostic yields of pre-biopsy brushing cytology, bronchial biopsy and subsequent brushing cytology were 17.2 (5/29), 75.9 (22/29) and 79.3 (23/29) percentage, respectively. The overall diagnostic sensitivity of biopsy, with the addition of post-biopsy brushing cytology, approached 93.1 percent. A better diagnostic yield of post-biopsy brushing cytology could be obtained as compared to pre-biopsy brushing cytology through a fiberoptic bronchoscope for endobronchial lesions. We concluded that a higher yield of brushing cytology following biopsy might be due to the exposure of submucosal cancer cells. Our data support the notion of combined use of bronchial biopsy and subsequent brushing cytology for the diagnosis of endobronchial lesions." @default.
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- W2419515402 date "1997-12-01" @default.
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- W2419515402 title "Comparison of the Diagnostic Yield of Bronchial Brushing Cytology before and after Endobronchial Biopsy of Flexible Fiberoptic Bronchoscopy-A Prospective Study" @default.
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