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- W2419619781 abstract "To study the effects of benzene exposure on chromosome aberration of peripheral lymphocytes in workers.Measure the benzene concentration with 3M passive dosimetry badges and analyze chromosome aberrations of peripheral lymphocytes using non-banding method.The numerically aberrated cell rate of the workers exposed by benzene [13.00% (2.50%-21.00%)] was significantly higher than that of the controls [10.50% (3.50%-18.00%)] (P < 0.05), and the aberrated cell rate (excluded gaps) [14.50% (5.00%-23.50%)] was significantly higher than that of the controls [11.75(3.50-18.00)] (P < 0.05), too; the P values of the dose-effect relationships between hyperploidy cell rate, numerically aberrated cell rate and aberrated cell rate (excluded gaps) and 8 h-TWA were 0.0008, 0.3741 and 0.2816, respectively, and the P values of the dose-effect relationships between those and the cumulative exposure were 0.0009, 0.0376 and 0.0486, respectively; the premature centromere division cell rate of the benzene-exposed workers [1.75% (0-19.50%)] was not significantly higher than that of the controls [1.00% (0-15.00%)] (P > 0.05).Benzene exposure resulted in an increase of chromosome aberrations of the peripheral lymphocytes, which was in a dose-effect relationship manner; whether benzene exposure could induce premature centromere division deserves further studies." @default.
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- W2419619781 date "2004-05-01" @default.
- W2419619781 modified "2023-09-27" @default.
- W2419619781 title "[Chromosome aberration analysis of peripheral lymphocytes in workers exposed to benzene]." @default.
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