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- W2419662044 abstract "Summary Degradation products of human fibrinogen were prepared by in vitro lysis of fibrin clots by urokinase activation and injected into rabbits on a quantitative basis. The dose necessary to anticoagulate the animal was equal to 2½ to 3 times the animals’ fibrinogen level. The effect on whole blood clotting time and thrombin time lasted for approximately 2 hrs. The “r” time of the TEG returned to normal after 1 hr while the “Max” value remained abnormal for more than 120 min. Degradation product E was shown to clear more rapidly than D by immunochemical techniques. The overall T ½ clearance was found to be approximately 12 hrs." @default.
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- W2419662044 date "1970-01-01" @default.
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- W2419662044 title "Quantitation of the Coagulation Inhibition in Vivo Due to Breakdown Products of Fibrin" @default.
- W2419662044 doi "https://doi.org/10.1055/s-0038-1654074" @default.
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