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- W2419830192 abstract "This report will focus on a combined treatment of the fields of evolution and DNA computers. Using examples of in vitro selection of functional molecules from large pools of random sequences, I show that these experiments can be viewed as an RNA computer, in the language of DNA computation. By applying a strict set of criteria to a pool of heterogeneous DNA or sequences, both types of experiments find sequences that contain solutions to hard computational problems. These can even be nondigital problems that an electronic computer cannot solve. For example, a problem I addressed using a pool of molecules was one of catalysis, or the ability to ligate a small substrate molecule to itself. In vitro evolution searches for the best solution or class of solutions contained within a large library of approximately 10^15 unique sequences. The advantage of these molecular computers is their ability to examine and eliminate billions of possible solutions in parallel. We also describe an example of a cellular paradigm for RNA-based computing: editing. From the Second Annual DIMACS Meeting on DNA Based Computers, June 10-12, 1996 and the DIMACS Special Focus on DNA Computing." @default.
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- W2419830192 date "1997-12-20" @default.
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- W2419830192 title "RNA Based Computing" @default.
- W2419830192 hasPublicationYear "1997" @default.
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