Matches in SemOpenAlex for { <https://semopenalex.org/work/W2419902648> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2419902648 endingPage "55" @default.
- W2419902648 startingPage "346" @default.
- W2419902648 abstract "Using two antibodies raised against Paramecium axonemal tubulin, a monoclonal antibody, AXO 49 (Callen et al., Biol. Cell 81, 95-119 (1994)), and a polyclonal antibody, PAT (Cohen et al., Biol. Cell 44, 35-44 (1982)), which have been shown elsewhere to detect a new posttranslational modification of tubulin presumably corresponding to polyglycylation, we have analyzed the occurrence of this modification during spermatogenesis in Drosophila. Results obtained by immunofluorescence on cysts isolated by laceration of testes showed that the antibodies reacted on axonemal microtubules of several species within the genus. Observation of different stages of differentiation of D. obscura sperm cells indicated, first, that the epitopes reactive with both antibodies appeared at late stages, and secondly, that they were detected simultaneously along all axonemes within a cyst. Immunofluorescence on semithin sections and electron microscopic immunocytochemistry on ultrathin sections confirmed that the appearance of the epitope recognized by the monoclonal antibody occurred at the time of the individualization process of spermatids in D. melanogaster. These results indicate that the posttranslational modification occurs as a very late event, after complete assembly of axonemal microtubules, and that the axonemal tubulin becomes modified when axonemal microtubules become coupled with the membrane, suggesting that the modification may in some way be induced by the microtubule-membrane interaction." @default.
- W2419902648 created "2016-06-24" @default.
- W2419902648 creator A5000043890 @default.
- W2419902648 creator A5016530776 @default.
- W2419902648 creator A5035324157 @default.
- W2419902648 creator A5067181339 @default.
- W2419902648 creator A5070826735 @default.
- W2419902648 creator A5089935748 @default.
- W2419902648 date "1995-08-01" @default.
- W2419902648 modified "2023-09-25" @default.
- W2419902648 title "A massive new posttranslational modification occurs on axonemal tubulin at the final step of spermatogenesis in Drosophila." @default.
- W2419902648 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8521874" @default.
- W2419902648 hasPublicationYear "1995" @default.
- W2419902648 type Work @default.
- W2419902648 sameAs 2419902648 @default.
- W2419902648 citedByCount "9" @default.
- W2419902648 countsByYear W24199026482018 @default.
- W2419902648 crossrefType "journal-article" @default.
- W2419902648 hasAuthorship W2419902648A5000043890 @default.
- W2419902648 hasAuthorship W2419902648A5016530776 @default.
- W2419902648 hasAuthorship W2419902648A5035324157 @default.
- W2419902648 hasAuthorship W2419902648A5067181339 @default.
- W2419902648 hasAuthorship W2419902648A5070826735 @default.
- W2419902648 hasAuthorship W2419902648A5089935748 @default.
- W2419902648 hasConcept C104317684 @default.
- W2419902648 hasConcept C115811362 @default.
- W2419902648 hasConcept C134018914 @default.
- W2419902648 hasConcept C153911025 @default.
- W2419902648 hasConcept C159654299 @default.
- W2419902648 hasConcept C195616568 @default.
- W2419902648 hasConcept C20418707 @default.
- W2419902648 hasConcept C24870808 @default.
- W2419902648 hasConcept C2778236600 @default.
- W2419902648 hasConcept C2780104201 @default.
- W2419902648 hasConcept C35866371 @default.
- W2419902648 hasConcept C542903549 @default.
- W2419902648 hasConcept C54355233 @default.
- W2419902648 hasConcept C61081601 @default.
- W2419902648 hasConcept C84425145 @default.
- W2419902648 hasConcept C86803240 @default.
- W2419902648 hasConcept C95444343 @default.
- W2419902648 hasConcept C956191 @default.
- W2419902648 hasConceptScore W2419902648C104317684 @default.
- W2419902648 hasConceptScore W2419902648C115811362 @default.
- W2419902648 hasConceptScore W2419902648C134018914 @default.
- W2419902648 hasConceptScore W2419902648C153911025 @default.
- W2419902648 hasConceptScore W2419902648C159654299 @default.
- W2419902648 hasConceptScore W2419902648C195616568 @default.
- W2419902648 hasConceptScore W2419902648C20418707 @default.
- W2419902648 hasConceptScore W2419902648C24870808 @default.
- W2419902648 hasConceptScore W2419902648C2778236600 @default.
- W2419902648 hasConceptScore W2419902648C2780104201 @default.
- W2419902648 hasConceptScore W2419902648C35866371 @default.
- W2419902648 hasConceptScore W2419902648C542903549 @default.
- W2419902648 hasConceptScore W2419902648C54355233 @default.
- W2419902648 hasConceptScore W2419902648C61081601 @default.
- W2419902648 hasConceptScore W2419902648C84425145 @default.
- W2419902648 hasConceptScore W2419902648C86803240 @default.
- W2419902648 hasConceptScore W2419902648C95444343 @default.
- W2419902648 hasConceptScore W2419902648C956191 @default.
- W2419902648 hasIssue "4" @default.
- W2419902648 hasLocation W24199026481 @default.
- W2419902648 hasOpenAccess W2419902648 @default.
- W2419902648 hasPrimaryLocation W24199026481 @default.
- W2419902648 hasRelatedWork W1616748355 @default.
- W2419902648 hasRelatedWork W1969470151 @default.
- W2419902648 hasRelatedWork W2042435075 @default.
- W2419902648 hasRelatedWork W2068999859 @default.
- W2419902648 hasRelatedWork W2079716855 @default.
- W2419902648 hasRelatedWork W2094263173 @default.
- W2419902648 hasRelatedWork W2113394908 @default.
- W2419902648 hasRelatedWork W2419902648 @default.
- W2419902648 hasRelatedWork W2431832318 @default.
- W2419902648 hasRelatedWork W2403097654 @default.
- W2419902648 hasVolume "67" @default.
- W2419902648 isParatext "false" @default.
- W2419902648 isRetracted "false" @default.
- W2419902648 magId "2419902648" @default.
- W2419902648 workType "article" @default.