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- W2420199272 abstract "<b><i>Objectives:</i></b> Abdominal aortic aneurysm (AAA) is a pathological condition characterized by an abnormal, localized dilatation of the lower part of the aorta. Due to a lack of data on the natural history of AAA and risk of death from other cardiovascular diseases attributable to AAA, the true number of AAA-attributable deaths may be higher than currently estimated. This study aims to produce more realistic estimates of the burden of AAA. <b><i>Methods:</i></b> A disease-modeling software, DisMod II, was used to assess the AAA burden via a multistate life table. Inputs included population, all-cause mortality, size- and sex-specific AAA prevalence, and relative risk of death estimates for persons with AAA compared with persons without AAA. <b><i>Results:</i></b> There were 2,347,339 prevalent cases of AAA in the USA in 2013 (95% CI: 2,131,964-2,524,116), resulting in 41,371 deaths attributable to AAA (95% CI: 34,090-49,234). Females constituted 21.1% of prevalent cases and 45.2% of deaths, compared with males constituting 78.9% of prevalent cases and 54.8% of deaths. <b><i>Conclusions:</i></b> This work shows that the burden of mortality attributable to AAA is more than twice the current estimates from the American Heart Association. Females account for a disproportionately high percentage of deaths despite constituting a low percentage of prevalent cases." @default.
- W2420199272 created "2016-06-24" @default.
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- W2420199272 date "2016-01-01" @default.
- W2420199272 modified "2023-09-24" @default.
- W2420199272 title "Modeling the Burden of Abdominal Aortic Aneurysm in the USA in 2013" @default.
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- W2420199272 doi "https://doi.org/10.1159/000446871" @default.
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