FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2420666807> ?p ?o ?g. }

• W2420666807 endingPage "1758" @default.
• W2420666807 startingPage "1749" @default.
• W2420666807 abstract "Essentials It is unclear if thrombophilia increases the risk of catheter-associated thrombosis in children. We conducted a meta-analysis on thrombophilia and pediatric catheter-associated thrombosis. Presence of ≥1 trait confers additional risk of venous thrombosis in children with catheters. Limitations of included studies preclude us from recommending routine thrombophilia testing.Background The association between thrombophilia and deep vein thrombosis (DVT) associated with central venous catheter (CVC) use, the most important pediatric risk factor for thrombosis, is unclear in children. Pediatric studies with small sample sizes have reported conflicting results. We sought to evaluate whether, among children with CVCs, thrombophilia increases the risk of CVC-associated DVT (CADVT). Materials and methods We systematically searched MEDLINE, EMBASE, the Web of Science, the Cochrane Central Register for Controlled Trials, PubMed and reference lists for controlled studies published from the inception of the database until September 2015. Included were studies of children aged <21 years with CVCs who were systematically tested for thrombophilic traits that are commonly screened for in clinical practice. Pooled prevalence rates and pooled odds ratios (pORs) of CADVT with thrombophilia were estimated by use of a random effects model. Results We analyzed 16 cohort studies with 1279 children, 277 of whom had CADVT, and with 12 traits tested. There was significant heterogeneity in the included studies. The presence of one or more traits was associated with CADVT (pOR 3.20; 95% confidence interval [CI] 1.56-6.54). Although the prevalence of most traits was < 0.10, children with protein C deficiency, elevated factor VIII levels and the FV Leiden mutation had an increased prevalence of CADVT. The association with thrombophilia seemed to be stronger for symptomatic CADVT (pOR 6.71; 95% CI 1.93-23.37) than for asymptomatic CADVT (pOR 2.14; 95% CI 1.10-4.18). Conclusions On the basis of the low prevalence of specific traits, the relatively weak association with CADVT, and the limitations of the included studies, we cannot recommend routine testing of thrombophilias in children with CADVT." @default.
• W2420666807 created "2016-06-24" @default.
• W2420666807 creator A5056348530 @default.
• W2420666807 creator A5059671221 @default.
• W2420666807 creator A5064364327 @default.
• W2420666807 creator A5087610068 @default.
• W2420666807 creator A5089576056 @default.
• W2420666807 date "2016-09-01" @default.
• W2420666807 modified "2023-10-10" @default.
• W2420666807 title "Association of thrombophilia and catheter‐associated thrombosis in children: a systematic review and meta‐analysis" @default.
• W2420666807 cites W1564175447 @default.
• W2420666807 cites W1574141134 @default.
• W2420666807 cites W1967696348 @default.
• W2420666807 cites W1974885634 @default.
• W2420666807 cites W1975092417 @default.
• W2420666807 cites W1979423827 @default.
• W2420666807 cites W1979987466 @default.
• W2420666807 cites W1983000651 @default.
• W2420666807 cites W1983017124 @default.
• W2420666807 cites W1995132478 @default.
• W2420666807 cites W1998397662 @default.
• W2420666807 cites W2004988702 @default.
• W2420666807 cites W2016544425 @default.
• W2420666807 cites W2027254548 @default.
• W2420666807 cites W2028182349 @default.
• W2420666807 cites W2029524694 @default.
• W2420666807 cites W2045816462 @default.
• W2420666807 cites W2048453223 @default.
• W2420666807 cites W2052109409 @default.
• W2420666807 cites W2059635862 @default.
• W2420666807 cites W2059914591 @default.
• W2420666807 cites W2068291350 @default.
• W2420666807 cites W2072311684 @default.
• W2420666807 cites W2079213131 @default.
• W2420666807 cites W2093141344 @default.
• W2420666807 cites W2098065872 @default.
• W2420666807 cites W2098923148 @default.
• W2420666807 cites W2100994130 @default.
• W2420666807 cites W2106459062 @default.
• W2420666807 cites W2107252782 @default.
• W2420666807 cites W2107328434 @default.
• W2420666807 cites W2111649707 @default.
• W2420666807 cites W2112879444 @default.
• W2420666807 cites W2115086661 @default.
• W2420666807 cites W2122916891 @default.
• W2420666807 cites W2125435699 @default.
• W2420666807 cites W2134852288 @default.
• W2420666807 cites W2143881211 @default.
• W2420666807 cites W2162051878 @default.
• W2420666807 cites W2163661402 @default.
• W2420666807 cites W2164313674 @default.
• W2420666807 cites W2415908113 @default.
• W2420666807 cites W2418770240 @default.
• W2420666807 cites W2588681363 @default.
• W2420666807 doi "https://doi.org/10.1111/jth.13388" @default.
• W2420666807 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5035642" @default.
• W2420666807 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27306795" @default.
• W2420666807 hasPublicationYear "2016" @default.
• W2420666807 type Work @default.
• W2420666807 sameAs 2420666807 @default.
• W2420666807 citedByCount "30" @default.
• W2420666807 countsByYear W24206668072016 @default.
• W2420666807 countsByYear W24206668072017 @default.
• W2420666807 countsByYear W24206668072018 @default.
• W2420666807 countsByYear W24206668072019 @default.
• W2420666807 countsByYear W24206668072020 @default.
• W2420666807 countsByYear W24206668072021 @default.
• W2420666807 countsByYear W24206668072022 @default.
• W2420666807 crossrefType "journal-article" @default.
• W2420666807 hasAuthorship W2420666807A5056348530 @default.
• W2420666807 hasAuthorship W2420666807A5059671221 @default.
• W2420666807 hasAuthorship W2420666807A5064364327 @default.
• W2420666807 hasAuthorship W2420666807A5087610068 @default.
• W2420666807 hasAuthorship W2420666807A5089576056 @default.
• W2420666807 hasBestOaLocation W24206668071 @default.
• W2420666807 hasConcept C126322002 @default.
• W2420666807 hasConcept C156957248 @default.
• W2420666807 hasConcept C187212893 @default.
• W2420666807 hasConcept C2777175894 @default.
• W2420666807 hasConcept C2780011451 @default.
• W2420666807 hasConcept C2780842393 @default.
• W2420666807 hasConcept C2780868729 @default.
• W2420666807 hasConcept C44249647 @default.
• W2420666807 hasConcept C50440223 @default.
• W2420666807 hasConcept C71924100 @default.
• W2420666807 hasConcept C95190672 @default.
• W2420666807 hasConceptScore W2420666807C126322002 @default.
• W2420666807 hasConceptScore W2420666807C156957248 @default.
• W2420666807 hasConceptScore W2420666807C187212893 @default.
• W2420666807 hasConceptScore W2420666807C2777175894 @default.
• W2420666807 hasConceptScore W2420666807C2780011451 @default.
• W2420666807 hasConceptScore W2420666807C2780842393 @default.
• W2420666807 hasConceptScore W2420666807C2780868729 @default.
• W2420666807 hasConceptScore W2420666807C44249647 @default.
• W2420666807 hasConceptScore W2420666807C50440223 @default.
• W2420666807 hasConceptScore W2420666807C71924100 @default.
• W2420666807 hasConceptScore W2420666807C95190672 @default.
• W2420666807 hasFunder F4320306230 @default.

• next