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• W2421870885 abstract "HomeRadiologyVol. 40, No. 4 PreviousNext EditorialAtypical (Virus) PneumoniaPublished Online:Apr 1 1943https://doi.org/10.1148/40.4.408MoreSectionsPDF ToolsImage ViewerAdd to favoritesCiteTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinked In AbstractDuring the past seven years there have appeared in the medical literature a number of reports of pneumonia cases which reacted atypically and from which no absolute etiologic agent could be isolated. As these reports were studied and observations were correlated, a clear-cut clinical picture emerged, so that a diagnosis was possible even in the absence of etiologic proof. Numerous names have been applied to this condition, of which “virus pneumonia” and “atypical bronchopneumonia” are in more common use.This unusual and relatively new syndrome was the subject of a complete symposium at the Annual Meeting of the Radiological Society of North America, in 1942. The papers comprising that symposium are published in this issue of Radiology. We wish here to call attention to them and to indicate briefly some of the salient points which are brought out.The etiology has been one of the most elusive factors in the proper classification of this condition. Rhoads calls attention to the fact that several viruses may be active agents in epidemics of the disease. One virus which was isolated bore a close relationship to the viruses of lymphogranuloma venereum and psittacosis. It has been found, also, that the virus can readily be transmitted from one mongoose to another, though ordinary laboratory animals show a high degree of resistance. Rhoads was able to transmit the disease from a patient to a mouse and thence to other mice. The culture showed evidence of Streptococcus viridans. Unfiltered material was found to produce much more pronounced changes in the lungs of mice than the same material after filtration.Saphir describes the difficulty, from the pathologist's standpoint, of proving a virus to be the unquestionable etiologic agent. He points out that many believe that the influenza epidemic of 1918–19 was of virus origin and that the presence of organisms in the sputum does not rule out the simultaneous presence of a virus which may have been the sole cause of the disease. It is well known that virus diseases are highly contagious and are especially dangerous to laboratory workers. Saphir found the lung changes to consist essentially of an interstitial pneumonia, although in the more severe cases the alveoli are also involved. The exudate consists mostly of mononuclear elements, in contrast to that of lobar or bronchopneumonia. When the alveoli become involved, a hyaline-like ring forms within them, thus interfering with the free exchange of gases.There is a rather general agreement among all observers as to the clinical picture in these cases. Many of the patients are not extremely ill and recover rapidly with minimum physical and roentgen signs. Those who are more severely ill usually have a dry, unproductive cough, with chilliness rather than true chills, fever, and general malaise.Article HistoryPublished in print: Apr 1943 FiguresReferencesRelatedDetailsRecommended Articles RSNA Education Exhibits RSNA Case Collection Vol. 40, No. 4 Metrics Altmetric Score PDF download" @default.
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• W2421870885 date "1943-04-01" @default.
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• W2421870885 title "Atypical (Virus) Pneumonia" @default.
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