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• W2424352702 abstract "ABSTRACTPurpose: Although the rabbit eye is of a similar size to the human eye, our limited understanding of the differences in retinal physiology to other species hinders its use in retinal research. The role of voltage-gated sodium channels (Nav) in the propagation of excitatory potentials along bipolar cells remains unclear, as conflicting data have been reported in the rabbit. The present study assesses the relative contributions of Nav to the scotopic and photopic flash ERGs as well as the wavelength-dependence of Nav blockade on the rabbit flicker ERG.Materials and Methods: Tetrodotoxin (TTX, 1 μM) was injected into the vitreous cavity of Chinchilla bastard rabbits. Scotopic ERGs were evoked by white flashes ranging from 10−5 to 10 cds m−2, photopic ERGs on a background of 25 cdm−2 using flash intensities of 0.032–25 cds m−2. Flicker ERGs (3–50 Hz) were elicited by blue, green and yellow stimuli at 2.34 cds m−2 on a white background of 30 cdm−2.Results: The a- and b-waves of the scotopic ERG were un..." @default.
• W2424352702 created "2016-06-24" @default.
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• W2424352702 date "2015-05-14" @default.
• W2424352702 modified "2023-09-25" @default.
• W2424352702 title "Contribution of Voltage-Gated Sodium Channels to the Rabbit Cone Electroretinograms" @default.
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• W2424352702 doi "https://doi.org/10.3109/02713683.2015.1029134" @default.
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