Matches in SemOpenAlex for { <https://semopenalex.org/work/W2424378207> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2424378207 endingPage "5" @default.
- W2424378207 startingPage "1502" @default.
- W2424378207 abstract "Interleukin-12 plays an important role in anti-tumor immune response by induction of interferon-gamma production by T cells and NK cells, and by activation of cytotoxic T cells and NK cells. We evaluated interleukin-12-induced interferon-gamma production as one of the immunological markers of patients with chronic liver diseases.Interleukin-12-induced interferon-gamma production was measured in vitro in peripheral blood mononuclear cells from 28 hepatocellular carcinoma patients, 10 liver cirrhosis patients, 14 chronic hepatitis patients and 16 healthy individuals.The hepatocellular carcinoma patients exhibited a reduced interleukin-12 responsiveness for interferon-gamma production compared to the liver cirrhosis patients, the chronic hepatitis patients and the healthy individuals. The reduced interferon-gamma production seemed to roughly reflect clinical stage in the hepatocellular carcinoma patients. The interferon-gamma production correlated with neither alpha-fetoprotein nor protein induced by vitamin K absence II.The level of interleukin-12-induced interferon-gamma production by peripheral blood mononuclear cells in the patients with hepatocellular carcinoma was significantly lower than that in the patients with liver cirrhosis which is thought to be a premalignant state. The measurement of interferon-gamma production may be useful in evaluating severity of chronic liver disease from an immunological point of view." @default.
- W2424378207 created "2016-06-24" @default.
- W2424378207 creator A5001357732 @default.
- W2424378207 creator A5006148805 @default.
- W2424378207 creator A5007883181 @default.
- W2424378207 creator A5023348385 @default.
- W2424378207 creator A5024249304 @default.
- W2424378207 creator A5033063072 @default.
- W2424378207 creator A5048897631 @default.
- W2424378207 creator A5052022288 @default.
- W2424378207 creator A5057548461 @default.
- W2424378207 creator A5081487421 @default.
- W2424378207 creator A5090201638 @default.
- W2424378207 date "2003-10-24" @default.
- W2424378207 modified "2023-10-03" @default.
- W2424378207 title "Evaluation of interleukin-12-induced interferon-y production in vitro by peripheral blood mononuclear cells in patients with chronic liver disease." @default.
- W2424378207 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14571773" @default.
- W2424378207 hasPublicationYear "2003" @default.
- W2424378207 type Work @default.
- W2424378207 sameAs 2424378207 @default.
- W2424378207 citedByCount "1" @default.
- W2424378207 crossrefType "journal-article" @default.
- W2424378207 hasAuthorship W2424378207A5001357732 @default.
- W2424378207 hasAuthorship W2424378207A5006148805 @default.
- W2424378207 hasAuthorship W2424378207A5007883181 @default.
- W2424378207 hasAuthorship W2424378207A5023348385 @default.
- W2424378207 hasAuthorship W2424378207A5024249304 @default.
- W2424378207 hasAuthorship W2424378207A5033063072 @default.
- W2424378207 hasAuthorship W2424378207A5048897631 @default.
- W2424378207 hasAuthorship W2424378207A5052022288 @default.
- W2424378207 hasAuthorship W2424378207A5057548461 @default.
- W2424378207 hasAuthorship W2424378207A5081487421 @default.
- W2424378207 hasAuthorship W2424378207A5090201638 @default.
- W2424378207 hasConcept C126322002 @default.
- W2424378207 hasConcept C137061746 @default.
- W2424378207 hasConcept C202751555 @default.
- W2424378207 hasConcept C203014093 @default.
- W2424378207 hasConcept C2776178377 @default.
- W2424378207 hasConcept C2777075537 @default.
- W2424378207 hasConcept C2777214474 @default.
- W2424378207 hasConcept C2778019345 @default.
- W2424378207 hasConcept C2778690821 @default.
- W2424378207 hasConcept C2779102576 @default.
- W2424378207 hasConcept C2780841837 @default.
- W2424378207 hasConcept C55493867 @default.
- W2424378207 hasConcept C71924100 @default.
- W2424378207 hasConcept C74172505 @default.
- W2424378207 hasConcept C86803240 @default.
- W2424378207 hasConceptScore W2424378207C126322002 @default.
- W2424378207 hasConceptScore W2424378207C137061746 @default.
- W2424378207 hasConceptScore W2424378207C202751555 @default.
- W2424378207 hasConceptScore W2424378207C203014093 @default.
- W2424378207 hasConceptScore W2424378207C2776178377 @default.
- W2424378207 hasConceptScore W2424378207C2777075537 @default.
- W2424378207 hasConceptScore W2424378207C2777214474 @default.
- W2424378207 hasConceptScore W2424378207C2778019345 @default.
- W2424378207 hasConceptScore W2424378207C2778690821 @default.
- W2424378207 hasConceptScore W2424378207C2779102576 @default.
- W2424378207 hasConceptScore W2424378207C2780841837 @default.
- W2424378207 hasConceptScore W2424378207C55493867 @default.
- W2424378207 hasConceptScore W2424378207C71924100 @default.
- W2424378207 hasConceptScore W2424378207C74172505 @default.
- W2424378207 hasConceptScore W2424378207C86803240 @default.
- W2424378207 hasIssue "53" @default.
- W2424378207 hasLocation W24243782071 @default.
- W2424378207 hasOpenAccess W2424378207 @default.
- W2424378207 hasPrimaryLocation W24243782071 @default.
- W2424378207 hasRelatedWork W2006454743 @default.
- W2424378207 hasRelatedWork W2011030389 @default.
- W2424378207 hasRelatedWork W2021790244 @default.
- W2424378207 hasRelatedWork W2065825827 @default.
- W2424378207 hasRelatedWork W2127439791 @default.
- W2424378207 hasRelatedWork W2159002152 @default.
- W2424378207 hasRelatedWork W2186365449 @default.
- W2424378207 hasRelatedWork W2424378207 @default.
- W2424378207 hasRelatedWork W2954945993 @default.
- W2424378207 hasRelatedWork W3147373859 @default.
- W2424378207 hasVolume "50" @default.
- W2424378207 isParatext "false" @default.
- W2424378207 isRetracted "false" @default.
- W2424378207 magId "2424378207" @default.
- W2424378207 workType "article" @default.