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• W2424504129 abstract "ADHD and asthma are prevalent conditions in childhood, with complex pathophysiology involving genetic-environmental interplay. The study objective is to examine the prevalence of asthma in our ADHD population and explore factors that may increase the risk of developing asthma in children with ADHD.We retrospectively analyzed the presence of maternal stress during pregnancy and history of asthma in 201 children diagnosed with ADHD.Chi-square analysis indicated significant higher presence of asthma in our ADHD sample compared to Quebec children, χ(2)(1, N = 201) = 15.37, P<0.001. Only prematurity and stress during pregnancy significantly predicted asthma in a logistic regression model, χ(2)(2)=23.70, P<0.001, with odds ratios of 10.6 (95% CI: 2.8-39.5) and 3.2 (95% CI: 1.4-7.3), respectively.Children with ADHD have a higher prevalence of asthma than the general Quebec pediatric population. Children with ADHD born prematurely and/or those whose mothers experienced stress during pregnancy have a significantly increased risk of developing asthma. The study highlights the importance of potentially offering social and psychological support to mothers who experienced stress during pregnancy and/or are at risk of delivering prematurely.Le TDAH et l’asthme sont des affections prévalentes dans l’enfance, avec une pathophysiologie complexe impliquant une interaction génétique-environnementale. L’étude vise à examiner la prévalence de l’asthme dans notre population TDAH et à explorer les facteurs qui peuvent accroître le risque de développer l’asthme chez les enfants souffrant du TDAH.Nous avons analysé rétrospectivement la présence de stress maternel durant la grossesse et les antécédents d’asthme chez 201 enfants ayant reçu un diagnostic de TDAH.L’analyse du chi-carré a indiqué la présence significativement plus élevée d’asthme dans notre échantillon TDAH comparativement aux enfants du Québec, χ2 (1, N = 201) = 15,37; P<0,001. Seuls la prématurité et le stress maternel durant la grossesse prédisaient significativement l’asthme dans un modèle de régression logistique, χ2(2) = 23,70; P<0,001, avec des rapports de cotes de 10,6 (IC à 95% 2,8 à 39,5) et de 3,2 (IC à 95% 1,4 à 7,3), respectivement.Les enfants souffrant du TDAH ont une prévalence d’asthme plus élevée que la population pédiatrique générale du Québec. Les enfants souffrant du TDAH nés prématurément et/ou ceux dont les mères ont éprouvé du stress durant la grossesse ont un risque significativement accru de développer l’asthme. L’étude souligne l’importance d’offrir potentiellement un soutien psychologique et social aux mères qui éprouvent du stress durant la grossesse et/ou sont à risque d’accoucher prématurément." @default.
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• W2424504129 date "2015-01-01" @default.
• W2424504129 modified "2023-09-23" @default.
• W2424504129 title "Increased Risk of Asthma in Children with ADHD: Role of Prematurity and Maternal Stress during Pregnancy." @default.
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