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- W2424589701 abstract "Affinity chromatography is ideally suited to the purification of pharmaceutical proteins due to its unique bio-specificity characteristics. Tailor-made affinity ligands that represent a promising class of synthetic affinity ligands have been developed to target specific proteins and designed to mimic peptidal templates, natural biological recognition motifs, or complementary surface-exposed residues. These biomimetic ligands have been generated by a combination of rational design, combinatorial library synthesis, and subsequent screening of potential leads against target proteins. Small ligands based on a triazine scaffold also present exceptional selectivity and stability, which allows their use in harsh manufacturing environments." @default.
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- W2424589701 date "2005-01-01" @default.
- W2424589701 modified "2023-09-23" @default.
- W2424589701 title "Design, Synthesis, and Screening of Biomimetic Ligands for Affinity Chromatography" @default.
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- W2424589701 doi "https://doi.org/10.1007/978-1-59259-948-6_4" @default.
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