FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2425107450> ?p ?o ?g. }

• W2425107450 endingPage "3999" @default.
• W2425107450 startingPage "3991" @default.
• W2425107450 abstract "The binding of propidium to poly(dA).poly(dT) [poly(dA.dT)] and to poly[d(A-T)].poly[d(A-T)] [poly[d(A-T)2]] has been compared under a variety of solution conditions by viscometric titrations, binding studies, and kinetic experiments. The binding of propidium to poly[d(A-T)2] is quite similar to its binding to calf thymus deoxyribonucleic acid (DNA). The interaction with poly(dA.dT), however, is quite unusual. The viscosity of a poly(dA.dT) solution first decreases and then increases in a titration with propidium at 18 degrees C. The viscosity of poly[d(A-T)2] shows no decrease in a similar titration. Scatchard plots for the interaction of propidium with poly(dA.dT) show the classical upward curvature for positive cooperativity. The curvature decreases as the temperature is increased in binding experiments. A van't Hoff plot of the observed binding constants yields an apparent positive enthalpy of approximately +6 kcal/mol for the propidium-poly(dA.dT) interaction. Propidium binding to poly[d(A-T)2] shows no evidence for positive cooperativity, and the enthalpy change for the reaction is approximately -9 kcal/mol. Both the magnitude of the dissociation constants and the effects of ionic strength are quite similar for the dissociation of propidium from poly(dA-T)2] and from poly[d(A-T)2], suggesting that the intercalated states are similar for the two complexes. The observed association reactions, under pseudo-first-order conditions, are quite different. Plots of the observed pseudo-first-order association rate constant vs. polymer concentration have much larger slopes for propidium binding to poly[d(A-T)2] than to poly(dA.dT).(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
• W2425107450 created "2016-06-24" @default.
• W2425107450 creator A5013036455 @default.
• W2425107450 creator A5013955348 @default.
• W2425107450 creator A5030624539 @default.
• W2425107450 creator A5083623044 @default.
• W2425107450 date "1985-07-01" @default.
• W2425107450 modified "2023-09-24" @default.
• W2425107450 title "Poly(dA).cntdot.poly(dT) exists in an unusual conformation under physiological conditions: propidium binding to poly(dA).cntdot.poly(dT) and poly[d(A-T)].cntdot.poly[d(A-T)]" @default.
• W2425107450 cites W127867126 @default.
• W2425107450 cites W1515668612 @default.
• W2425107450 cites W1964243769 @default.
• W2425107450 cites W1964606787 @default.
• W2425107450 cites W1989246398 @default.
• W2425107450 cites W1989651677 @default.
• W2425107450 cites W1998150847 @default.
• W2425107450 cites W2009208424 @default.
• W2425107450 cites W2010521445 @default.
• W2425107450 cites W2022211160 @default.
• W2425107450 cites W2025146752 @default.
• W2425107450 cites W2026039391 @default.
• W2425107450 cites W2026884660 @default.
• W2425107450 cites W2030223140 @default.
• W2425107450 cites W2038874225 @default.
• W2425107450 cites W2040577917 @default.
• W2425107450 cites W2044000024 @default.
• W2425107450 cites W2051242936 @default.
• W2425107450 cites W2064445937 @default.
• W2425107450 cites W2066703244 @default.
• W2425107450 cites W2073787422 @default.
• W2425107450 cites W2086158633 @default.
• W2425107450 cites W2092426779 @default.
• W2425107450 cites W2106978502 @default.
• W2425107450 cites W2126466006 @default.
• W2425107450 cites W2164129750 @default.
• W2425107450 cites W2415282745 @default.
• W2425107450 cites W2950152787 @default.
• W2425107450 doi "https://doi.org/10.1021/bi00336a029" @default.
• W2425107450 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4052380" @default.
• W2425107450 hasPublicationYear "1985" @default.
• W2425107450 type Work @default.
• W2425107450 sameAs 2425107450 @default.
• W2425107450 citedByCount "102" @default.
• W2425107450 countsByYear W24251074502012 @default.
• W2425107450 countsByYear W24251074502013 @default.
• W2425107450 countsByYear W24251074502014 @default.
• W2425107450 countsByYear W24251074502015 @default.
• W2425107450 countsByYear W24251074502018 @default.
• W2425107450 countsByYear W24251074502022 @default.
• W2425107450 crossrefType "journal-article" @default.
• W2425107450 hasAuthorship W2425107450A5013036455 @default.
• W2425107450 hasAuthorship W2425107450A5013955348 @default.
• W2425107450 hasAuthorship W2425107450A5030624539 @default.
• W2425107450 hasAuthorship W2425107450A5083623044 @default.
• W2425107450 hasConcept C107824862 @default.
• W2425107450 hasConcept C121332964 @default.
• W2425107450 hasConcept C147789679 @default.
• W2425107450 hasConcept C166014724 @default.
• W2425107450 hasConcept C184866935 @default.
• W2425107450 hasConcept C185592680 @default.
• W2425107450 hasConcept C187250156 @default.
• W2425107450 hasConcept C190283241 @default.
• W2425107450 hasConcept C2775934118 @default.
• W2425107450 hasConcept C31573885 @default.
• W2425107450 hasConcept C3288061 @default.
• W2425107450 hasConcept C55493867 @default.
• W2425107450 hasConcept C8010536 @default.
• W2425107450 hasConcept C97355855 @default.
• W2425107450 hasConceptScore W2425107450C107824862 @default.
• W2425107450 hasConceptScore W2425107450C121332964 @default.
• W2425107450 hasConceptScore W2425107450C147789679 @default.
• W2425107450 hasConceptScore W2425107450C166014724 @default.
• W2425107450 hasConceptScore W2425107450C184866935 @default.
• W2425107450 hasConceptScore W2425107450C185592680 @default.
• W2425107450 hasConceptScore W2425107450C187250156 @default.
• W2425107450 hasConceptScore W2425107450C190283241 @default.
• W2425107450 hasConceptScore W2425107450C2775934118 @default.
• W2425107450 hasConceptScore W2425107450C31573885 @default.
• W2425107450 hasConceptScore W2425107450C3288061 @default.
• W2425107450 hasConceptScore W2425107450C55493867 @default.
• W2425107450 hasConceptScore W2425107450C8010536 @default.
• W2425107450 hasConceptScore W2425107450C97355855 @default.
• W2425107450 hasIssue "15" @default.
• W2425107450 hasLocation W24251074501 @default.
• W2425107450 hasLocation W24251074502 @default.
• W2425107450 hasOpenAccess W2425107450 @default.
• W2425107450 hasPrimaryLocation W24251074501 @default.
• W2425107450 hasRelatedWork W118085161 @default.
• W2425107450 hasRelatedWork W1997135566 @default.
• W2425107450 hasRelatedWork W1997422604 @default.
• W2425107450 hasRelatedWork W2058035240 @default.
• W2425107450 hasRelatedWork W2064358068 @default.
• W2425107450 hasRelatedWork W2066444220 @default.
• W2425107450 hasRelatedWork W2088416676 @default.
• W2425107450 hasRelatedWork W2532807154 @default.
• W2425107450 hasRelatedWork W2587784901 @default.
• W2425107450 hasRelatedWork W4241787150 @default.
• W2425107450 hasVolume "24" @default.

• next