Matches in SemOpenAlex for { <https://semopenalex.org/work/W2425408989> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W2425408989 endingPage "211" @default.
- W2425408989 startingPage "206" @default.
- W2425408989 abstract "Aims: The aim of this report is to review the literature concerning atypical adenomatous hyperplasia (AAH) with specific regard to evidence in support of or refuting its role as a precursor lesion for prostatic adenocarcinoma. Methods: The available literature was collected and critically reviewed. In addition, recently reported (abstract) but as yet unpublished data were included. Particular attention was focused on biological studies. Results: There is considerable morphologic evidence suggesting that AAH is associated with low-grade (Gleason patterns 1 and 2) adenocarcinoma arising in the transition zone. Only limited biologic studies have been performed. There is weak and limited data to indicate that AAH has a proliferation rate higher than hyperplasia but lower than adenocarcinoma. AAH is diploid, as are most examples of low-grade adenocarcinoma. A few markers (blood group antigens, peanut agglutinin) show similar patems of expression in AAH and adenocarcinoma while others (carbohydrate D-galactose-N-acetyl-.D-galactosamine) do not. Recent cytogenetic analyses have detected abnormalities of chromosome 8 in a very small proportion (4-6%) of cases of AAH studied. Conclusions: Presently, the only strong evidence linking AAH to adenocarcinoma is morphologic. The few biologic and molecular/cytogenetic studies performed have not provided convincing evidence to support or refute this possibility. Additional studies are required. Finally, in comparative studies of AAH with adenocarcinoma, the latter should include low-grade transition zone tumors." @default.
- W2425408989 created "2016-06-24" @default.
- W2425408989 creator A5014281092 @default.
- W2425408989 creator A5027009066 @default.
- W2425408989 date "1996-01-01" @default.
- W2425408989 modified "2023-10-06" @default.
- W2425408989 title "Atypical Adenomatous Hyperplasia of the Prostate: A Critical Review" @default.
- W2425408989 doi "https://doi.org/10.1159/000474171" @default.
- W2425408989 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8875202" @default.
- W2425408989 hasPublicationYear "1996" @default.
- W2425408989 type Work @default.
- W2425408989 sameAs 2425408989 @default.
- W2425408989 citedByCount "38" @default.
- W2425408989 countsByYear W24254089892012 @default.
- W2425408989 countsByYear W24254089892014 @default.
- W2425408989 countsByYear W24254089892018 @default.
- W2425408989 crossrefType "journal-article" @default.
- W2425408989 hasAuthorship W2425408989A5014281092 @default.
- W2425408989 hasAuthorship W2425408989A5027009066 @default.
- W2425408989 hasConcept C121608353 @default.
- W2425408989 hasConcept C126322002 @default.
- W2425408989 hasConcept C142724271 @default.
- W2425408989 hasConcept C2777150480 @default.
- W2425408989 hasConcept C2777562237 @default.
- W2425408989 hasConcept C2780814781 @default.
- W2425408989 hasConcept C2781182431 @default.
- W2425408989 hasConcept C526805850 @default.
- W2425408989 hasConcept C71924100 @default.
- W2425408989 hasConceptScore W2425408989C121608353 @default.
- W2425408989 hasConceptScore W2425408989C126322002 @default.
- W2425408989 hasConceptScore W2425408989C142724271 @default.
- W2425408989 hasConceptScore W2425408989C2777150480 @default.
- W2425408989 hasConceptScore W2425408989C2777562237 @default.
- W2425408989 hasConceptScore W2425408989C2780814781 @default.
- W2425408989 hasConceptScore W2425408989C2781182431 @default.
- W2425408989 hasConceptScore W2425408989C526805850 @default.
- W2425408989 hasConceptScore W2425408989C71924100 @default.
- W2425408989 hasIssue "2" @default.
- W2425408989 hasLocation W24254089891 @default.
- W2425408989 hasLocation W24254089892 @default.
- W2425408989 hasOpenAccess W2425408989 @default.
- W2425408989 hasPrimaryLocation W24254089891 @default.
- W2425408989 hasRelatedWork W1978595424 @default.
- W2425408989 hasRelatedWork W1993223855 @default.
- W2425408989 hasRelatedWork W2042461862 @default.
- W2425408989 hasRelatedWork W2076552859 @default.
- W2425408989 hasRelatedWork W2138437337 @default.
- W2425408989 hasRelatedWork W2423183512 @default.
- W2425408989 hasRelatedWork W297936465 @default.
- W2425408989 hasRelatedWork W3024583666 @default.
- W2425408989 hasRelatedWork W3098419952 @default.
- W2425408989 hasRelatedWork W3119088194 @default.
- W2425408989 hasVolume "30" @default.
- W2425408989 isParatext "false" @default.
- W2425408989 isRetracted "false" @default.
- W2425408989 magId "2425408989" @default.
- W2425408989 workType "article" @default.