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- W2425431567 abstract "The electron-microscopic study revealed that nephritogenic E. coli having L-mannose-resistant fimbriae contacted with subcultured human renal cells due to the interaction of fimbriae with microvilli and, less frequently, with the cytoplasmic membrane surrounding the main part of the cell, as well as with the electron-opaque fibrillar material in the intercellular space. The possibility of very close interaction was demonstrated; in some cases this interaction was so close that the outlines of bacterial and epitheloid cells followed each other, the invagination of the external membrane of the host cell being sometimes observed. The expediency of using ruthenium red for detecting fimbriae in morphological studies was shown. The cytopathogenic effect observed in this study and developing by the end of the 5-hour period from the moment of the inoculation of the monolayer with E. coli was manifested by the swelling of mitochondria accompanied by the partial ruptures of cristae, the widening of channels in the endoplasmic reticulum, the appearance of the secondary lysosomes and the increase of their number." @default.
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- W2425431567 date "1983-07-01" @default.
- W2425431567 modified "2023-09-23" @default.
- W2425431567 title "[Electron microscopic study of the interaction of nephritogenic strains of Escherichia coli carrying D-mannose-resistant fimbriae with the cells of a human kidney line]." @default.
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