Matches in SemOpenAlex for { <https://semopenalex.org/work/W2425456502> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2425456502 endingPage "2172" @default.
- W2425456502 startingPage "2163" @default.
- W2425456502 abstract "Background: A meta-analysis of the risk of selected gastrointestinal and hepatic toxicities associated with nintedanib has been conducted. Methods: Randomized Phase II/III trials of cancer patients on nintedanib; describing events of diarrhea, vomiting, elevated ALT and elevated AST constituted the eligible studies. Results: The odds ratio for high-grade diarrhea was 3.76 (95% CI: 1.42–9.96; p = 0.008); high-grade vomiting: 1.38 (95% CI: 0.76–2.51; p = 0.28); high-grade elevated ALT: 4.36 (95% CI: 2.14–8.85; p < 0.0001); high-grade elevated AST: 6.96 (95% CI: 4.09–11.85; p < 0.00001). Conclusion: Nintedanib-based regimens are associated with a higher risk of high-grade diarrhea, elevated ALT and elevated AST. Moreover, there is a proportional relationship between nintedanib dose and the risk of elevated transaminases." @default.
- W2425456502 created "2016-06-24" @default.
- W2425456502 creator A5070907022 @default.
- W2425456502 creator A5082810931 @default.
- W2425456502 creator A5089122189 @default.
- W2425456502 date "2016-09-01" @default.
- W2425456502 modified "2023-10-18" @default.
- W2425456502 title "Risk of selected gastrointestinal and hepatic toxicities in cancer patients treated with nintedanib: a meta-analysis" @default.
- W2425456502 cites W173418661 @default.
- W2425456502 cites W1952173328 @default.
- W2425456502 cites W1981608915 @default.
- W2425456502 cites W1981980118 @default.
- W2425456502 cites W1984776467 @default.
- W2425456502 cites W1994016697 @default.
- W2425456502 cites W2005501262 @default.
- W2425456502 cites W2010589478 @default.
- W2425456502 cites W2047377282 @default.
- W2425456502 cites W2065902287 @default.
- W2425456502 cites W2078592499 @default.
- W2425456502 cites W2099753110 @default.
- W2425456502 cites W2100405674 @default.
- W2425456502 cites W2105121109 @default.
- W2425456502 cites W2105246037 @default.
- W2425456502 cites W2118256381 @default.
- W2425456502 cites W2126318680 @default.
- W2425456502 cites W2128178813 @default.
- W2425456502 cites W2162226026 @default.
- W2425456502 cites W2164134225 @default.
- W2425456502 cites W2170030318 @default.
- W2425456502 cites W2173776890 @default.
- W2425456502 cites W2197641370 @default.
- W2425456502 cites W2200887263 @default.
- W2425456502 cites W2238285053 @default.
- W2425456502 cites W2272757036 @default.
- W2425456502 cites W572470369 @default.
- W2425456502 doi "https://doi.org/10.2217/fon-2016-0067" @default.
- W2425456502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27301454" @default.
- W2425456502 hasPublicationYear "2016" @default.
- W2425456502 type Work @default.
- W2425456502 sameAs 2425456502 @default.
- W2425456502 citedByCount "4" @default.
- W2425456502 countsByYear W24254565022018 @default.
- W2425456502 countsByYear W24254565022019 @default.
- W2425456502 countsByYear W24254565022020 @default.
- W2425456502 crossrefType "journal-article" @default.
- W2425456502 hasAuthorship W2425456502A5070907022 @default.
- W2425456502 hasAuthorship W2425456502A5082810931 @default.
- W2425456502 hasAuthorship W2425456502A5089122189 @default.
- W2425456502 hasConcept C126322002 @default.
- W2425456502 hasConcept C156957248 @default.
- W2425456502 hasConcept C2777714996 @default.
- W2425456502 hasConcept C2778341716 @default.
- W2425456502 hasConcept C2779802037 @default.
- W2425456502 hasConcept C2780171596 @default.
- W2425456502 hasConcept C2780852908 @default.
- W2425456502 hasConcept C71924100 @default.
- W2425456502 hasConcept C90924648 @default.
- W2425456502 hasConceptScore W2425456502C126322002 @default.
- W2425456502 hasConceptScore W2425456502C156957248 @default.
- W2425456502 hasConceptScore W2425456502C2777714996 @default.
- W2425456502 hasConceptScore W2425456502C2778341716 @default.
- W2425456502 hasConceptScore W2425456502C2779802037 @default.
- W2425456502 hasConceptScore W2425456502C2780171596 @default.
- W2425456502 hasConceptScore W2425456502C2780852908 @default.
- W2425456502 hasConceptScore W2425456502C71924100 @default.
- W2425456502 hasConceptScore W2425456502C90924648 @default.
- W2425456502 hasIssue "18" @default.
- W2425456502 hasLocation W24254565021 @default.
- W2425456502 hasLocation W24254565022 @default.
- W2425456502 hasOpenAccess W2425456502 @default.
- W2425456502 hasPrimaryLocation W24254565021 @default.
- W2425456502 hasRelatedWork W2008662664 @default.
- W2425456502 hasRelatedWork W2021331582 @default.
- W2425456502 hasRelatedWork W2069907756 @default.
- W2425456502 hasRelatedWork W2080294143 @default.
- W2425456502 hasRelatedWork W2096612642 @default.
- W2425456502 hasRelatedWork W2368596924 @default.
- W2425456502 hasRelatedWork W2468258954 @default.
- W2425456502 hasRelatedWork W2751339230 @default.
- W2425456502 hasRelatedWork W4220669495 @default.
- W2425456502 hasRelatedWork W4255361753 @default.
- W2425456502 hasVolume "12" @default.
- W2425456502 isParatext "false" @default.
- W2425456502 isRetracted "false" @default.
- W2425456502 magId "2425456502" @default.
- W2425456502 workType "article" @default.