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• W2425687041 abstract "Contrast-enhanced digital subtraction (CEDS) imaging refers to radiological techniques based on the use of a contrast medium (generally iodinated) to increase the contrast between organs of interest and background anatomy in medical images. In this work, a commercial microCT (voltage range 30-45 kV, not specifically designed for quantitative studies) was characterized for use in preclinical CEDS quantitative studies. The characterization of the system consisted of quantifying and optimizing the performance of the X-ray tube and detector. The optimization was done on 2D images. A protocol to acquire original images (pre-subtraction) based on the characterization was established. The protocol faced the detector limitations, such as lack of stability of the response and non-uniformity in images of homogeneous objects. Radiological techniques (voltage and additional filtering) for studies with CEDS were optimized. Single energy temporal (SET) and dual energy (DE) subtractions modalities were studied. The opti..." @default.
• W2425687041 created "2016-06-24" @default.
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• W2425687041 date "2016-01-01" @default.
• W2425687041 modified "2023-10-18" @default.
• W2425687041 title "A method to optimize the image acquisition protocol of a MicroCT unit for preclinical studies using contrast-enhanced digital subtraction" @default.
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• W2425687041 doi "https://doi.org/10.1063/1.4954123" @default.
• W2425687041 hasPublicationYear "2016" @default.
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