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- W2425700460 abstract "The fission yeast model system Schizosaccharomyces pombe is used to study fundamental biological processes. To continue to fill gaps in the Sz. pombe gene deletion collection, we constructed a set of 90 haploid gene deletion strains covering many previously uncharacterized genes. To begin to understand the function of these genes, we exposed this collection of strains to a battery of stress conditions. Using this information in combination with microscopy, proteomics and mini-chromosome loss assays, we identified genes involved in cell wall integrity, cytokinesis, chromosome segregation and DNA metabolism. This subset of non-essential gene deletions will add to the toolkits available for the study of biological processes in Sz. pombe. Copyright © 2016 John Wiley & Sons, Ltd." @default.
- W2425700460 created "2016-06-24" @default.
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- W2425700460 date "2016-06-29" @default.
- W2425700460 modified "2023-10-14" @default.
- W2425700460 title "Discovery of genes involved in mitosis, cell division, cell wall integrity and chromosome segregation through construction of<i>Schizosaccharomyces pombe</i>deletion strains" @default.
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- W2425700460 doi "https://doi.org/10.1002/yea.3172" @default.
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