Matches in SemOpenAlex for { <https://semopenalex.org/work/W2425861710> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2425861710 endingPage "9, 1223" @default.
- W2425861710 startingPage "1216" @default.
- W2425861710 abstract "To investigate the effects of different microenvironments on the differentiation of mouse induced pluripotent stem cells (iPSCs) into neuron-like cells.Mouse iPSCs were cultured in suspension and became embryoid bodies (EBs), and then the EBs were randomly divided into all-trans-retinoic acid (ATRA) group, brain slice co-culture group, and brain tissue homogenate supernatant group. The above three groups were induced to differentiate into neuron-like cells. Morphological changes were observed under an inverted microscope. Immunofluorescence staining technology was used for cell identification. The expressions of nestin, microtubule-associated protein 2 (MAP2) and glial fibrillary acidic protein (GFAP) were detected by Western blotting.The three different culture conditions could all induce mouse iPSCs to differentiate into neuron-like cells. These neuron-like cells could be marked by neuron markers like nestin and MAP2. The levels of nestin, MAP2 and GFAP proteins in the ATRA group were significantly higher than those in both the brain slice co-culture group and the brain tissue homogenate supernatant group, but there was no significant difference between the brain slice co-culture group and the brain tissue homogenate supernatant group.Both brain slice microenvironment and brain tissue homogenate supernatant can induce the differentiation of mouse iPSCs into neuron-like cells, but the effect is inferior to ATRA." @default.
- W2425861710 created "2016-06-24" @default.
- W2425861710 creator A5011300178 @default.
- W2425861710 creator A5045331018 @default.
- W2425861710 creator A5046214153 @default.
- W2425861710 creator A5058283264 @default.
- W2425861710 creator A5070626493 @default.
- W2425861710 creator A5082396860 @default.
- W2425861710 date "2015-09-01" @default.
- W2425861710 modified "2023-09-23" @default.
- W2425861710 title "[Inducing effects of different microenvironments on the differentiation of mouse induced pluripotent stem cells into neuron-like cells]." @default.
- W2425861710 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26359103" @default.
- W2425861710 hasPublicationYear "2015" @default.
- W2425861710 type Work @default.
- W2425861710 sameAs 2425861710 @default.
- W2425861710 citedByCount "0" @default.
- W2425861710 crossrefType "journal-article" @default.
- W2425861710 hasAuthorship W2425861710A5011300178 @default.
- W2425861710 hasAuthorship W2425861710A5045331018 @default.
- W2425861710 hasAuthorship W2425861710A5046214153 @default.
- W2425861710 hasAuthorship W2425861710A5058283264 @default.
- W2425861710 hasAuthorship W2425861710A5070626493 @default.
- W2425861710 hasAuthorship W2425861710A5082396860 @default.
- W2425861710 hasConcept C104317684 @default.
- W2425861710 hasConcept C107459253 @default.
- W2425861710 hasConcept C136834591 @default.
- W2425861710 hasConcept C143948831 @default.
- W2425861710 hasConcept C145103041 @default.
- W2425861710 hasConcept C148738053 @default.
- W2425861710 hasConcept C153911025 @default.
- W2425861710 hasConcept C162746124 @default.
- W2425861710 hasConcept C169760540 @default.
- W2425861710 hasConcept C203014093 @default.
- W2425861710 hasConcept C204232928 @default.
- W2425861710 hasConcept C20875687 @default.
- W2425861710 hasConcept C2777738006 @default.
- W2425861710 hasConcept C2778794669 @default.
- W2425861710 hasConcept C2780495277 @default.
- W2425861710 hasConcept C2781121885 @default.
- W2425861710 hasConcept C28328180 @default.
- W2425861710 hasConcept C54355233 @default.
- W2425861710 hasConcept C55493867 @default.
- W2425861710 hasConcept C81885089 @default.
- W2425861710 hasConcept C86803240 @default.
- W2425861710 hasConcept C95444343 @default.
- W2425861710 hasConceptScore W2425861710C104317684 @default.
- W2425861710 hasConceptScore W2425861710C107459253 @default.
- W2425861710 hasConceptScore W2425861710C136834591 @default.
- W2425861710 hasConceptScore W2425861710C143948831 @default.
- W2425861710 hasConceptScore W2425861710C145103041 @default.
- W2425861710 hasConceptScore W2425861710C148738053 @default.
- W2425861710 hasConceptScore W2425861710C153911025 @default.
- W2425861710 hasConceptScore W2425861710C162746124 @default.
- W2425861710 hasConceptScore W2425861710C169760540 @default.
- W2425861710 hasConceptScore W2425861710C203014093 @default.
- W2425861710 hasConceptScore W2425861710C204232928 @default.
- W2425861710 hasConceptScore W2425861710C20875687 @default.
- W2425861710 hasConceptScore W2425861710C2777738006 @default.
- W2425861710 hasConceptScore W2425861710C2778794669 @default.
- W2425861710 hasConceptScore W2425861710C2780495277 @default.
- W2425861710 hasConceptScore W2425861710C2781121885 @default.
- W2425861710 hasConceptScore W2425861710C28328180 @default.
- W2425861710 hasConceptScore W2425861710C54355233 @default.
- W2425861710 hasConceptScore W2425861710C55493867 @default.
- W2425861710 hasConceptScore W2425861710C81885089 @default.
- W2425861710 hasConceptScore W2425861710C86803240 @default.
- W2425861710 hasConceptScore W2425861710C95444343 @default.
- W2425861710 hasIssue "9" @default.
- W2425861710 hasLocation W24258617101 @default.
- W2425861710 hasOpenAccess W2425861710 @default.
- W2425861710 hasPrimaryLocation W24258617101 @default.
- W2425861710 hasRelatedWork W2025192477 @default.
- W2425861710 hasRelatedWork W2040902558 @default.
- W2425861710 hasRelatedWork W2042342648 @default.
- W2425861710 hasRelatedWork W2050345055 @default.
- W2425861710 hasRelatedWork W2091223560 @default.
- W2425861710 hasRelatedWork W2137346763 @default.
- W2425861710 hasRelatedWork W2313271146 @default.
- W2425861710 hasRelatedWork W2318472435 @default.
- W2425861710 hasRelatedWork W2416444910 @default.
- W2425861710 hasRelatedWork W2425861710 @default.
- W2425861710 hasVolume "31" @default.
- W2425861710 isParatext "false" @default.
- W2425861710 isRetracted "false" @default.
- W2425861710 magId "2425861710" @default.
- W2425861710 workType "article" @default.