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• W2426274210 abstract "# Centralisation of care leads to better outcome {#article-title-2} Editor—The finding of a persistently poor outcome of pregnancy in women with insulin dependent diabetes in two (northern) English regions is an important statement of the problem.1 2 Both studies provide figures and show outcomes that are no different from those widely reported in the past. Unfortunately, neither give evidence of any degree of centralisation of obstetric or diabetic care, with on-site neonatal intensive care, although this is a proved means of improving the outcome of pregnancy for diabetic mothers.3 The St Vincent declaration guidelines on the outcome of pregnancy, referred to in the accompanying editorial (p 263), are based on the Scandinavian reports held up as examples of good practice and state that “an interdisciplinary team should provide centralized diabetic pregnancy care in a hospital treating at least 20–30 cases a year. Pregnant diabetic patients should regularly visit the centre, before, during, and after the pregnancy.” The combined diabetes pregnancy clinic at the Royal Maternity Hospital in Belfast has existed for over 40 years, and outcome audit has shown the value of this approach.4 In an audit of over 800 pregnancies in diabetic mothers identified in Northern Ireland over the past 10 years the perinatal mortality in mothers cared for throughout at this centralised clinic during 1985–95 was 27/1000, compared with 70/1000 for patients referred later in pregnancy and 33/1000 for those mothers cared for in other maternity hospitals in Northern Ireland. Overall perinatal mortality for the whole population of Northern Ireland (1.5 million) during this decade was 9.3/1000 total births, so that even at a centralised clinic there is still an increased risk in diabetic pregnancy. Centralisation of care and improved cooperation among the obstetricians and diabetes physicians within a health region will lead to a better outcome.5 1. 1.↵1. Casson IF, 2. Clarke CA, 3. Howard CV, 4. McKendrick O, 5. Pennycook S, 6. Pharoah POD, 7. et al . Outcomes of pregnancy in insulin dependent diabetic women: results of a five year population cohort study BMJ 1997;315:275–8. (2 August.) [OpenUrl][1][Abstract/FREE Full Text][2] 2. 2.↵1. Hawthorne G, 2. Robson S, 3. Ryall EA, 4. Sen D, 5. Roberts SH, 6. Ward Platt MP . Prospective population based survey of outcome of pregnancy in diabetic women: results of the Northern Diabetic Pregnancy Audit, 1994 BMJ 1997;315:279–81. (2 August.) [OpenUrl][3][Abstract/FREE Full Text][4] 3. 3.↵1. Harley JMG, 2. Montgomery DAD : Management of pregnancy complicated by diabetes. BMJ1965;i:14–6. 4. 4.↵1. Traub AI, 2. Harley JMG, 3. Cooper TK, 4. Maguiness S, 5. Hadden DR . Is centralized hospital care necessary for all insulin-dependent pregnant diabetics? Br Obstet Gynaecol 1987;94:957–62. [OpenUrl][5] 5. 5.↵1. Dornhorst A, 2. Hadden DR <!-- --> 1. Hadden DR : Diabetes in pregnancy: past, present and future. In: Dornhorst A, Hadden DR. Diabetes and pregnancy: an international approach to diagnosis and management. Chichester, Wiley, 1996:3–21. # Rate of congenital malformations is almost certainly gross underestimate {#article-title-8} Editor—Casson et al make several misrepresentations … [1]: {openurl}?query=rft.jtitle%253DBMJ%26rft.stitle%253DBMJ%26rft.issn%253D0007-1447%26rft.aulast%253DCasson%26rft.auinit1%253DI%2BF%26rft.volume%253D315%26rft.issue%253D7103%26rft.spage%253D275%26rft.epage%253D278%26rft.atitle%253DOutcomes%2Bof%2Bpregnancy%2Bin%2Binsulin%2Bdependent%2Bdiabetic%2Bwomen%253A%2Bresults%2Bof%2Ba%2Bfive%2Byear%2Bpopulation%2Bcohort%2Bstudy%26rft_id%253Dinfo%253Apmid%252F9274545%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/ijlink?linkType=ABST&journalCode=bmj&resid=315/7103/275&atom=%2Fbmj%2F316%2F7130%2F550.atom [3]: {openurl}?query=rft.jtitle%253DBMJ%26rft.stitle%253DBMJ%26rft.issn%253D0007-1447%26rft.aulast%253DHawthorne%26rft.auinit1%253DG.%26rft.volume%253D315%26rft.issue%253D7103%26rft.spage%253D279%26rft.epage%253D281%26rft.atitle%253DProspective%2Bpopulation%2Bbased%2Bsurvey%2Bof%2Boutcome%2Bof%2Bpregnancy%2Bin%2Bdiabetic%2Bwomen%253A%2Bresults%2Bof%2Bthe%2BNorthern%2BDiabetic%2BPregnancy%2BAudit%252C%2B1994%26rft_id%253Dinfo%253Apmid%252F9274546%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [4]: /lookup/ijlink?linkType=ABST&journalCode=bmj&resid=315/7103/279&atom=%2Fbmj%2F316%2F7130%2F550.atom [5]: {openurl}?query=rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx" @default.
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• W2426274210 title "Outcome of pregnancy in women with insulin dependent diabetes" @default.
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