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- W2426573120 abstract "头颈部鳞癌包括口腔颌面部肿瘤、喉癌、甲状腺癌、鼻咽癌等,是世界上常见恶性肿瘤之一。迄今确切的病因尚不清楚,可能是吸烟、饮酒、病毒感染等多种因素综合所致。尽管目前诊断手段、手术治疗及化疗水平比过去几十年都有提高,但头颈肿瘤5年的生存率仍然在50%左右。有文献报道,MicroRNA(miRNA)在多种人类肿瘤细胞中异常表达,并且参与调节肿瘤细胞的增殖、分化及凋亡等多个生物学过程,其突变、缺失或表达水平的异常与人类肿瘤的发生、发展密切相关。" @default.
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- W2426573120 date "2010-02-01" @default.
- W2426573120 modified "2023-09-25" @default.
- W2426573120 title "Research of microRNAs in head and neck cancer" @default.
- W2426573120 doi "https://doi.org/10.3760/cma.j.issn.1673-0860.2010.02.027" @default.
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