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- W2427447882 abstract "SummaryThe effect of vindesine was studied in 18 patients with metastasized testicular teratomas. All patients were previously treated with aggressive combination chemotherapy including vel-bane, bleomycin, adriamycin, cisplatinum, ifosfamide and VP 16. Of these 18 patients 10 patients received vindesine at 3–5 mg/m2/week as single doses (PR 50% = 1/10, NC = 3/10, PD = 6/10); 4/18 patients were treated with continuous infusion of vindesine (1.5-2 mg/m2/day for 3–4 days), with one patient obtaining a good partial response. Another 4 patients received vindesine-bleomycin combination chemotherapy as an alternative to Samuels’ regimen (PR 2/4, NC 2/4). In conclusion, vindesine has shown some activity in testicular cancer, but any superiority as compared with vinblastine cannot be derived from these data since they were obtained from heavily pretreated patients." @default.
- W2427447882 created "2016-06-24" @default.
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- W2427447882 date "1981-01-01" @default.
- W2427447882 modified "2023-09-23" @default.
- W2427447882 title "Investigations on the Possible Role of Vindesine in Chemotherapy for Testicular Teratomas" @default.
- W2427447882 doi "https://doi.org/10.1159/000428647" @default.
- W2427447882 hasPublicationYear "1981" @default.
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