Matches in SemOpenAlex for { <https://semopenalex.org/work/W2428011567> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2428011567 endingPage "7" @default.
- W2428011567 startingPage "472" @default.
- W2428011567 abstract "In a prospective study carried out during a three-week period in October 1998 in 13 teaching hospitals, 735 non-repetitive isolates of Pseudomonas aeruginosa were collected. In patients presenting cystic fibrosis (70 strains), the main serotypes isolated were O:6 (14.3%) and O:1 (14.3%). Serotypes O:11 and O:12 were exceptional. In other patients (665 strains), the most frequent serotypes were O:6 (15.9%), O:11 (15.6%), O:1 (10.7%) and O:12 (9.2%). The antibiotic susceptibility rates were as follows (respectively, non-cystic fibrosis and cystic fibrosis strains): ticarcillin, 55 and 59%, piperacillin, 71 and 67%, ceftazidime, 75 and 67%, cefepime, 56 and 43%, cefpirome, 37 and 21%, aztreonam, 57 and 56%, imipenem, 83 and 70%, amikacin, 69 and 33%, ciprofloxacin, 56 and 61% and fosfomycin, 33 and 43%. Serotype O:12 was the least susceptible to antibiotics. Forty-five percent of the non-cystic fibrosis strains presented intermediate susceptibility or resistance to ticarcillin. The most frequent mechanisms of resistance were: non-enzymatic resistance (14.3%), overproduction of the constitutive cephalosporinase (13.8%), production of transferable beta-lactamase (8.6%) and a combination of these mechanisms (4.2%). Among cystic fibrosis strains, resistance to beta-lactam antibiotics was mainly due to overproduction of the constitutive cephalosporinase (18.6%), whereas production of a transferable beta-lactamase was rare (1.4%). Susceptibility to aminoglycosides and fluoroquinolones was less frequent in isolates producing transferable beta-lactamases and/or overproducing cephalosporinase. Decreased susceptibility to imipenem was more frequent in strains presenting a high level of cephalosporinase production. Among the cephalosporins, cefepime was the least affected by the overproduction of constitutive cephalosporinase. Ceftazidime remained the most efficient antibiotic against both susceptible isolates and strains presenting a non-enzymatic or PSE-1 penicillinase-producing mechanism." @default.
- W2428011567 created "2016-06-24" @default.
- W2428011567 creator A5012276123 @default.
- W2428011567 creator A5014583080 @default.
- W2428011567 creator A5046163129 @default.
- W2428011567 date "2000-06-01" @default.
- W2428011567 modified "2023-09-23" @default.
- W2428011567 title "[Surveillance of Pseudomonas aeruginosa sensitivity to antibiotics in France and distribution of beta-lactam resistance mechanisms: 1998 GERPB study]." @default.
- W2428011567 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10949844" @default.
- W2428011567 hasPublicationYear "2000" @default.
- W2428011567 type Work @default.
- W2428011567 sameAs 2428011567 @default.
- W2428011567 citedByCount "8" @default.
- W2428011567 crossrefType "journal-article" @default.
- W2428011567 hasAuthorship W2428011567A5012276123 @default.
- W2428011567 hasAuthorship W2428011567A5014583080 @default.
- W2428011567 hasAuthorship W2428011567A5046163129 @default.
- W2428011567 hasConcept C126322002 @default.
- W2428011567 hasConcept C2776083883 @default.
- W2428011567 hasConcept C2776938444 @default.
- W2428011567 hasConcept C2776968632 @default.
- W2428011567 hasConcept C2777050379 @default.
- W2428011567 hasConcept C2777637488 @default.
- W2428011567 hasConcept C2778193466 @default.
- W2428011567 hasConcept C2778512257 @default.
- W2428011567 hasConcept C2778897966 @default.
- W2428011567 hasConcept C2779631663 @default.
- W2428011567 hasConcept C2780416669 @default.
- W2428011567 hasConcept C501593827 @default.
- W2428011567 hasConcept C523546767 @default.
- W2428011567 hasConcept C54355233 @default.
- W2428011567 hasConcept C71924100 @default.
- W2428011567 hasConcept C86803240 @default.
- W2428011567 hasConcept C89423630 @default.
- W2428011567 hasConcept C94665300 @default.
- W2428011567 hasConceptScore W2428011567C126322002 @default.
- W2428011567 hasConceptScore W2428011567C2776083883 @default.
- W2428011567 hasConceptScore W2428011567C2776938444 @default.
- W2428011567 hasConceptScore W2428011567C2776968632 @default.
- W2428011567 hasConceptScore W2428011567C2777050379 @default.
- W2428011567 hasConceptScore W2428011567C2777637488 @default.
- W2428011567 hasConceptScore W2428011567C2778193466 @default.
- W2428011567 hasConceptScore W2428011567C2778512257 @default.
- W2428011567 hasConceptScore W2428011567C2778897966 @default.
- W2428011567 hasConceptScore W2428011567C2779631663 @default.
- W2428011567 hasConceptScore W2428011567C2780416669 @default.
- W2428011567 hasConceptScore W2428011567C501593827 @default.
- W2428011567 hasConceptScore W2428011567C523546767 @default.
- W2428011567 hasConceptScore W2428011567C54355233 @default.
- W2428011567 hasConceptScore W2428011567C71924100 @default.
- W2428011567 hasConceptScore W2428011567C86803240 @default.
- W2428011567 hasConceptScore W2428011567C89423630 @default.
- W2428011567 hasConceptScore W2428011567C94665300 @default.
- W2428011567 hasIssue "5" @default.
- W2428011567 hasLocation W24280115671 @default.
- W2428011567 hasOpenAccess W2428011567 @default.
- W2428011567 hasPrimaryLocation W24280115671 @default.
- W2428011567 hasRelatedWork W1979120751 @default.
- W2428011567 hasRelatedWork W1999158795 @default.
- W2428011567 hasRelatedWork W2054148929 @default.
- W2428011567 hasRelatedWork W2123039222 @default.
- W2428011567 hasRelatedWork W2373680497 @default.
- W2428011567 hasRelatedWork W2391589371 @default.
- W2428011567 hasRelatedWork W2428011567 @default.
- W2428011567 hasRelatedWork W2914864931 @default.
- W2428011567 hasRelatedWork W2981811808 @default.
- W2428011567 hasRelatedWork W2462991878 @default.
- W2428011567 hasVolume "48" @default.
- W2428011567 isParatext "false" @default.
- W2428011567 isRetracted "false" @default.
- W2428011567 magId "2428011567" @default.
- W2428011567 workType "article" @default.