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- W2429139708 abstract "Cisplatin is widely used to treat a variety of cancers. However, ototoxicity and nephrotoxicity remain serious side effects of cisplatin-based chemotherapy. In order to inform the study of cisplatin's off-target effects, a new drug-fluorophore conjugate was synthesized that exhibited utility as a tracer to determine the cellular uptake and in vivo distribution of cisplatin. This probe will serve as a useful tool to facilitate investigations into the kinetics and biodistribution of cisplatin and its associated side effects in preclinical models after systemic administration." @default.
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- W2429139708 date "2016-06-24" @default.
- W2429139708 modified "2023-10-16" @default.
- W2429139708 title "Systemic Delivery and Biodistribution of Cisplatin <i>in Vivo</i>" @default.
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- W2429139708 doi "https://doi.org/10.1021/acs.molpharmaceut.6b00240" @default.
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