FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2429407625> ?p ?o ?g. }

• W2429407625 endingPage "9686" @default.
• W2429407625 startingPage "9681" @default.
• W2429407625 abstract "The secondary structures of calmodulin and parvalbumin are well established from X-ray diffraction and nuclear magnetic resonance spectroscopic studies, which indicate that these proteins are predominantly alpha-helical in character. Recent infrared studies have nevertheless suggested that the helical structures present in these proteins in solution are not the standard alpha-helix but rather some kind of distorted helices [Trewhella, J., et al. (1989) Biochemistry 28, 1294]. The evidence for this was the unusually low amide I frequency for calmodulin and troponin C in 2H2O solution. The studies presented here, however, suggest that the helical structures in these proteins are not significantly distorted, for two reasons. First, distorted helical structures have weaker hydrogen bonds than the standard alpha-helix and would therefore be expected to absorb at a higher rather than a lower frequency. Second, distorted helical structures would absorb at an unusual frequency in H2O solutions which is not the case for the proteins studied here. The band frequency of these proteins is observed to occur at a frequency observed with other proteins known to contain predominantly alpha-helical structures. Quantitative analysis of the FT-IR spectra of calmodulin (67% alpha-helix) and parvalbumin (68% alpha-helix) in H2O in the presence of Ca2+ gives helical contents similar to those reported by X-ray studies. This raises the question as to why these proteins in H2O show a normal frequency for the presence of alpha-helical structures and an abnormal frequency in 2H2O. Addition of deuterated glycerol to the proteins in 2H2O solutions results in a significant shift of absorbance to higher frequency.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
• W2429407625 created "2016-06-24" @default.
• W2429407625 creator A5006034052 @default.
• W2429407625 creator A5020176415 @default.
• W2429407625 creator A5077593543 @default.
• W2429407625 date "1991-10-08" @default.
• W2429407625 modified "2023-09-27" @default.
• W2429407625 title "Fourier transform infrared spectroscopic studies of calcium-binding proteins" @default.
• W2429407625 cites W1571243084 @default.
• W2429407625 cites W1934853983 @default.
• W2429407625 cites W1980720466 @default.
• W2429407625 cites W1995595779 @default.
• W2429407625 cites W2007506603 @default.
• W2429407625 cites W2011432954 @default.
• W2429407625 cites W2032370708 @default.
• W2429407625 cites W2037710668 @default.
• W2429407625 cites W2038088153 @default.
• W2429407625 cites W2044208863 @default.
• W2429407625 cites W2053591536 @default.
• W2429407625 cites W2069510735 @default.
• W2429407625 cites W2070510843 @default.
• W2429407625 cites W2073883999 @default.
• W2429407625 cites W2079564988 @default.
• W2429407625 cites W2082389960 @default.
• W2429407625 cites W2088107416 @default.
• W2429407625 cites W2090413444 @default.
• W2429407625 cites W2101522039 @default.
• W2429407625 cites W2110591420 @default.
• W2429407625 cites W2275822179 @default.
• W2429407625 cites W2048822096 @default.
• W2429407625 doi "https://doi.org/10.1021/bi00104a016" @default.
• W2429407625 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1911755" @default.
• W2429407625 hasPublicationYear "1991" @default.
• W2429407625 type Work @default.
• W2429407625 sameAs 2429407625 @default.
• W2429407625 citedByCount "141" @default.
• W2429407625 countsByYear W24294076252012 @default.
• W2429407625 countsByYear W24294076252013 @default.
• W2429407625 countsByYear W24294076252014 @default.
• W2429407625 countsByYear W24294076252015 @default.
• W2429407625 countsByYear W24294076252016 @default.
• W2429407625 countsByYear W24294076252017 @default.
• W2429407625 countsByYear W24294076252018 @default.
• W2429407625 countsByYear W24294076252019 @default.
• W2429407625 countsByYear W24294076252020 @default.
• W2429407625 countsByYear W24294076252021 @default.
• W2429407625 countsByYear W24294076252022 @default.
• W2429407625 countsByYear W24294076252023 @default.
• W2429407625 crossrefType "journal-article" @default.
• W2429407625 hasAuthorship W2429407625A5006034052 @default.
• W2429407625 hasAuthorship W2429407625A5020176415 @default.
• W2429407625 hasAuthorship W2429407625A5077593543 @default.
• W2429407625 hasConcept C118552586 @default.
• W2429407625 hasConcept C120665830 @default.
• W2429407625 hasConcept C121332964 @default.
• W2429407625 hasConcept C122229402 @default.
• W2429407625 hasConcept C133571119 @default.
• W2429407625 hasConcept C133927893 @default.
• W2429407625 hasConcept C141547260 @default.
• W2429407625 hasConcept C153642686 @default.
• W2429407625 hasConcept C15744967 @default.
• W2429407625 hasConcept C158355884 @default.
• W2429407625 hasConcept C169760540 @default.
• W2429407625 hasConcept C178790620 @default.
• W2429407625 hasConcept C184538305 @default.
• W2429407625 hasConcept C185592680 @default.
• W2429407625 hasConcept C18903297 @default.
• W2429407625 hasConcept C2778530040 @default.
• W2429407625 hasConcept C2779965526 @default.
• W2429407625 hasConcept C29688787 @default.
• W2429407625 hasConcept C36036425 @default.
• W2429407625 hasConcept C47701112 @default.
• W2429407625 hasConcept C500558357 @default.
• W2429407625 hasConcept C519063684 @default.
• W2429407625 hasConcept C55493867 @default.
• W2429407625 hasConcept C62614982 @default.
• W2429407625 hasConcept C8010536 @default.
• W2429407625 hasConcept C86803240 @default.
• W2429407625 hasConceptScore W2429407625C118552586 @default.
• W2429407625 hasConceptScore W2429407625C120665830 @default.
• W2429407625 hasConceptScore W2429407625C121332964 @default.
• W2429407625 hasConceptScore W2429407625C122229402 @default.
• W2429407625 hasConceptScore W2429407625C133571119 @default.
• W2429407625 hasConceptScore W2429407625C133927893 @default.
• W2429407625 hasConceptScore W2429407625C141547260 @default.
• W2429407625 hasConceptScore W2429407625C153642686 @default.
• W2429407625 hasConceptScore W2429407625C15744967 @default.
• W2429407625 hasConceptScore W2429407625C158355884 @default.
• W2429407625 hasConceptScore W2429407625C169760540 @default.
• W2429407625 hasConceptScore W2429407625C178790620 @default.
• W2429407625 hasConceptScore W2429407625C184538305 @default.
• W2429407625 hasConceptScore W2429407625C185592680 @default.
• W2429407625 hasConceptScore W2429407625C18903297 @default.
• W2429407625 hasConceptScore W2429407625C2778530040 @default.
• W2429407625 hasConceptScore W2429407625C2779965526 @default.
• W2429407625 hasConceptScore W2429407625C29688787 @default.
• W2429407625 hasConceptScore W2429407625C36036425 @default.
• W2429407625 hasConceptScore W2429407625C47701112 @default.

• next