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- W2429510502 abstract "Primary aldosteronism, first described in 1954 by Jerome Conn, was initially thought to be a rare disease but is now known to be the most prevalent curable form of arterial hypertension. According to findings from a recent meta-analysis, 1 Hannemann A Wallaschofski H Prevalence of primary aldosteronism in patient's cohorts and in population-based studies—a review of the current literature. Horm Metab Res. 2012; 44: 157-162 Crossref PubMed Scopus (248) Google Scholar 4·3% of patients with hypertension in primary care and 9·5% of those in referral centres have primary aldosteronism. Current guidelines recommend screening for primary aldosteronism in high-risk populations, including patients with sustained blood pressure more than 150/100 mm Hg, resistant hypertension, spontaneous or diuretic-induced hypokalaemia, adrenal incidentaloma, or sleep apnoea. 2 Funder JW Carey RM Mantero F et al. The management of primary aldosteronism: case detection, diagnosis, and treatment: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2016; 101: 1889-1916 Crossref PubMed Scopus (1439) Google Scholar Adrenal vein sampling versus CT scan to determine treatment in primary aldosteronism: an outcome-based randomised diagnostic trialTreatment of primary aldosteronism based on CT or AVS did not show significant differences in intensity of antihypertensive medication or clinical benefits for patients after 1 year of follow-up. This finding challenges the current recommendation to perform AVS in all patients with primary aldosteronism. Full-Text PDF" @default.
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- W2429510502 date "2016-09-01" @default.
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- W2429510502 title "Adrenal vein sampling for subtyping in primary aldosteronism" @default.
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- W2429510502 doi "https://doi.org/10.1016/s2213-8587(16)30113-9" @default.
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