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- W2429573609 abstract "A facile and convenient green click synthesis has been developed for the preparation of new fluorinated 1,2,3-triazoles under solvent-free conditions via a Huisgen 1,3-dipolar cycloaddition reaction between dimethylacetylene dicarboxylate (DMADC) and fluorophenyl azides in excellent yields within 2 min. Treatment of the resulting diesters with hydrazine hydrate furnished the corresponding dihydrazides, which, upon condensation with benzaldehyde derivatives, afforded a new series of bis-hydrazones. All of the synthesized compounds were fully characterized using infrared (IR) spectroscopy, 1H, 13C and 19F nuclear magnetic resonance (NMR), mass spectrometry (MS) and elemental analysis. A preliminary bioassay indicated that some of the tested compounds exhibited significant antimicrobial activity." @default.
- W2429573609 created "2016-06-24" @default.
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- W2429573609 date "2015-01-01" @default.
- W2429573609 modified "2023-09-25" @default.
- W2429573609 title "Efficient Eco-Friendly Solvent-Free Click Synthesis and Antimicrobial Evaluation of New Fluorinated 1,2,3-Triazoles and their Conversion into Schiff Bases" @default.
- W2429573609 doi "https://doi.org/10.5935/0103-5053.20150196" @default.
- W2429573609 hasPublicationYear "2015" @default.
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