Matches in SemOpenAlex for { <https://semopenalex.org/work/W2429620857> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2429620857 endingPage "G642" @default.
- W2429620857 startingPage "G639" @default.
- W2429620857 abstract "The effect of estrogens and androgens on hepatic glycolithocholate sulfotransferase activity was studied in male rats. Significant increases in specific activity were noted following treatment of rats for 21 days with 17 beta-estradiol, 17 alpha-ethynylestradiol, and the nonsteroidal estrogen agonists nafoxidine, tamoxifen, and diethylstilbestrol. Similar treatment of male rats with 5 alpha-dihydrotestosterone, hydrocortisone, norethindrone, and prolactin did not affect activity. To further assess the effect of androgens, male rats were castrated. Glycolithocholate sulfotransferase activity increased fivefold by 14 days after castration. Treatment of castrated rats with 5 alpha-dihydrotestosterone prevented the increase and maintained activity at the level of sham-operated animals. Castrated animals exhibited an additional increment in activity following treatment with 17 alpha-ethynylestradiol: specific activity in these animals rose to levels comparable with those measured in untreated female rats. These data suggest endogenous androgens maximally suppress hepatic glycolithocholate sulfotransferase activity in male rats. The data also indicate that activity is stimulated by estrogenic compounds of varied chemical structure and that stimulation is not solely due to suppression of androgen release by the testes as a consequence of estrogen treatment." @default.
- W2429620857 created "2016-06-24" @default.
- W2429620857 creator A5008600550 @default.
- W2429620857 creator A5065948849 @default.
- W2429620857 creator A5065959477 @default.
- W2429620857 date "1985-06-01" @default.
- W2429620857 modified "2023-09-26" @default.
- W2429620857 title "Androgens and estrogens affect hepatic bile acid sulfotransferase in male rats" @default.
- W2429620857 doi "https://doi.org/10.1152/ajpgi.1985.248.6.g639" @default.
- W2429620857 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3859225" @default.
- W2429620857 hasPublicationYear "1985" @default.
- W2429620857 type Work @default.
- W2429620857 sameAs 2429620857 @default.
- W2429620857 citedByCount "2" @default.
- W2429620857 crossrefType "journal-article" @default.
- W2429620857 hasAuthorship W2429620857A5008600550 @default.
- W2429620857 hasAuthorship W2429620857A5065948849 @default.
- W2429620857 hasAuthorship W2429620857A5065959477 @default.
- W2429620857 hasConcept C126322002 @default.
- W2429620857 hasConcept C134018914 @default.
- W2429620857 hasConcept C155138218 @default.
- W2429620857 hasConcept C185592680 @default.
- W2429620857 hasConcept C24998067 @default.
- W2429620857 hasConcept C2775904581 @default.
- W2429620857 hasConcept C2777164284 @default.
- W2429620857 hasConcept C2777911890 @default.
- W2429620857 hasConcept C2779064019 @default.
- W2429620857 hasConcept C2779256933 @default.
- W2429620857 hasConcept C2779881493 @default.
- W2429620857 hasConcept C2781397067 @default.
- W2429620857 hasConcept C55493867 @default.
- W2429620857 hasConcept C71315377 @default.
- W2429620857 hasConcept C71924100 @default.
- W2429620857 hasConcept C86803240 @default.
- W2429620857 hasConceptScore W2429620857C126322002 @default.
- W2429620857 hasConceptScore W2429620857C134018914 @default.
- W2429620857 hasConceptScore W2429620857C155138218 @default.
- W2429620857 hasConceptScore W2429620857C185592680 @default.
- W2429620857 hasConceptScore W2429620857C24998067 @default.
- W2429620857 hasConceptScore W2429620857C2775904581 @default.
- W2429620857 hasConceptScore W2429620857C2777164284 @default.
- W2429620857 hasConceptScore W2429620857C2777911890 @default.
- W2429620857 hasConceptScore W2429620857C2779064019 @default.
- W2429620857 hasConceptScore W2429620857C2779256933 @default.
- W2429620857 hasConceptScore W2429620857C2779881493 @default.
- W2429620857 hasConceptScore W2429620857C2781397067 @default.
- W2429620857 hasConceptScore W2429620857C55493867 @default.
- W2429620857 hasConceptScore W2429620857C71315377 @default.
- W2429620857 hasConceptScore W2429620857C71924100 @default.
- W2429620857 hasConceptScore W2429620857C86803240 @default.
- W2429620857 hasIssue "6" @default.
- W2429620857 hasLocation W24296208571 @default.
- W2429620857 hasLocation W24296208572 @default.
- W2429620857 hasOpenAccess W2429620857 @default.
- W2429620857 hasPrimaryLocation W24296208571 @default.
- W2429620857 hasRelatedWork W1968690445 @default.
- W2429620857 hasRelatedWork W1981433740 @default.
- W2429620857 hasRelatedWork W2017681441 @default.
- W2429620857 hasRelatedWork W2023266651 @default.
- W2429620857 hasRelatedWork W2027210979 @default.
- W2429620857 hasRelatedWork W2045166305 @default.
- W2429620857 hasRelatedWork W2057542808 @default.
- W2429620857 hasRelatedWork W2116250211 @default.
- W2429620857 hasRelatedWork W2411839432 @default.
- W2429620857 hasRelatedWork W2429620857 @default.
- W2429620857 hasVolume "248" @default.
- W2429620857 isParatext "false" @default.
- W2429620857 isRetracted "false" @default.
- W2429620857 magId "2429620857" @default.
- W2429620857 workType "article" @default.