Matches in SemOpenAlex for { <https://semopenalex.org/work/W2430544025> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2430544025 endingPage "47" @default.
- W2430544025 startingPage "S2" @default.
- W2430544025 abstract "Recent advances in accuracy and reliability of continuous glucose monitoring (CGM) devices have focused renewed interest on the use of such technology for therapeutic dosing of insulin without the need for independent confirmatory blood glucose meter measurements. An important issue that remains is the susceptibility of CGM devices to erroneous readings in the presence of common pharmacologic interferences. We report on a new method of assessing CGM sensor error to pharmacologic interferences using the example of oral administration of acetaminophen.We examined the responses of several different Food and Drug Administration-approved and commercially available CGM systems (Dexcom [San Diego, CA] Seven(®) Plus™, Medtronic Diabetes [Northridge, CA] Guardian(®), and Dexcom G4(®) Platinum) to oral acetaminophen in 10 healthy volunteers without diabetes. Microdialysis catheters were placed in the abdominal subcutaneous tissue. Blood and microdialysate samples were collected periodically and analyzed for glucose and acetaminophen concentrations before and after oral ingestion of 1 g of acetaminophen. We compared the response of CGM sensors with the measured acetaminophen concentrations in the blood and interstitial fluid.Although plasma glucose concentrations remained constant at approximately 90 mg/dL (approximately 5 mM) throughout the study, CGM glucose measurements varied between approximately 85 to 400 mg/dL (from approximately 5 to 22 mM) due to interference from the acetaminophen. The temporal profile of CGM interference followed acetaminophen concentrations measured in interstitial fluid (ISF).This is the first direct measurement of ISF concentrations of putative CGM interferences with simultaneous measurements of CGM performance in the presence of the interferences. The observed interference with glucose measurements in the tested CGM devices coincided temporally with appearance of acetaminophen in the ISF. The method applied here can be used to determine the susceptibility of current and future CGM systems to interference from acetaminophen or other exogenous pharmacologic agents." @default.
- W2430544025 created "2016-06-24" @default.
- W2430544025 creator A5000711891 @default.
- W2430544025 creator A5004580811 @default.
- W2430544025 creator A5036998784 @default.
- W2430544025 creator A5043696489 @default.
- W2430544025 creator A5048891213 @default.
- W2430544025 date "2016-02-01" @default.
- W2430544025 modified "2023-10-12" @default.
- W2430544025 title "Direct Evidence of Acetaminophen Interference with Subcutaneous Glucose Sensing in Humans: A Pilot Study" @default.
- W2430544025 cites W1171229282 @default.
- W2430544025 cites W1929144650 @default.
- W2430544025 cites W1986584937 @default.
- W2430544025 cites W1989350580 @default.
- W2430544025 cites W2034084425 @default.
- W2430544025 cites W2035642677 @default.
- W2430544025 cites W2076721326 @default.
- W2430544025 cites W2115532997 @default.
- W2430544025 cites W2147302321 @default.
- W2430544025 cites W2158434788 @default.
- W2430544025 cites W2165138941 @default.
- W2430544025 cites W2313689199 @default.
- W2430544025 doi "https://doi.org/10.1089/dia.2015.0410" @default.
- W2430544025 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4717519" @default.
- W2430544025 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26784129" @default.
- W2430544025 hasPublicationYear "2016" @default.
- W2430544025 type Work @default.
- W2430544025 sameAs 2430544025 @default.
- W2430544025 citedByCount "60" @default.
- W2430544025 countsByYear W24305440252016 @default.
- W2430544025 countsByYear W24305440252017 @default.
- W2430544025 countsByYear W24305440252018 @default.
- W2430544025 countsByYear W24305440252019 @default.
- W2430544025 countsByYear W24305440252020 @default.
- W2430544025 countsByYear W24305440252021 @default.
- W2430544025 countsByYear W24305440252022 @default.
- W2430544025 countsByYear W24305440252023 @default.
- W2430544025 crossrefType "journal-article" @default.
- W2430544025 hasAuthorship W2430544025A5000711891 @default.
- W2430544025 hasAuthorship W2430544025A5004580811 @default.
- W2430544025 hasAuthorship W2430544025A5036998784 @default.
- W2430544025 hasAuthorship W2430544025A5043696489 @default.
- W2430544025 hasAuthorship W2430544025A5048891213 @default.
- W2430544025 hasBestOaLocation W24305440251 @default.
- W2430544025 hasConcept C126322002 @default.
- W2430544025 hasConcept C134018914 @default.
- W2430544025 hasConcept C2778722691 @default.
- W2430544025 hasConcept C2779306644 @default.
- W2430544025 hasConcept C42219234 @default.
- W2430544025 hasConcept C50156730 @default.
- W2430544025 hasConcept C529278444 @default.
- W2430544025 hasConcept C555293320 @default.
- W2430544025 hasConcept C71924100 @default.
- W2430544025 hasConcept C98274493 @default.
- W2430544025 hasConceptScore W2430544025C126322002 @default.
- W2430544025 hasConceptScore W2430544025C134018914 @default.
- W2430544025 hasConceptScore W2430544025C2778722691 @default.
- W2430544025 hasConceptScore W2430544025C2779306644 @default.
- W2430544025 hasConceptScore W2430544025C42219234 @default.
- W2430544025 hasConceptScore W2430544025C50156730 @default.
- W2430544025 hasConceptScore W2430544025C529278444 @default.
- W2430544025 hasConceptScore W2430544025C555293320 @default.
- W2430544025 hasConceptScore W2430544025C71924100 @default.
- W2430544025 hasConceptScore W2430544025C98274493 @default.
- W2430544025 hasIssue "S2" @default.
- W2430544025 hasLocation W24305440251 @default.
- W2430544025 hasLocation W24305440252 @default.
- W2430544025 hasLocation W24305440253 @default.
- W2430544025 hasLocation W24305440254 @default.
- W2430544025 hasOpenAccess W2430544025 @default.
- W2430544025 hasPrimaryLocation W24305440251 @default.
- W2430544025 hasRelatedWork W1563850031 @default.
- W2430544025 hasRelatedWork W2032287785 @default.
- W2430544025 hasRelatedWork W2094113608 @default.
- W2430544025 hasRelatedWork W2167444163 @default.
- W2430544025 hasRelatedWork W2233866314 @default.
- W2430544025 hasRelatedWork W2383009242 @default.
- W2430544025 hasRelatedWork W2415759662 @default.
- W2430544025 hasRelatedWork W2549135832 @default.
- W2430544025 hasRelatedWork W3036934084 @default.
- W2430544025 hasRelatedWork W88627568 @default.
- W2430544025 hasVolume "18" @default.
- W2430544025 isParatext "false" @default.
- W2430544025 isRetracted "false" @default.
- W2430544025 magId "2430544025" @default.
- W2430544025 workType "article" @default.