Matches in SemOpenAlex for { <https://semopenalex.org/work/W2431053606> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2431053606 endingPage "94" @default.
- W2431053606 startingPage "87" @default.
- W2431053606 abstract "The effects of beta-carotene (beta C) or vitamin A (VA) administration for 8 consecutive weeks were compared in male Wistar rats submitted to the resistant hepatocyte model (RH model) of hepatocarcinogenesis. Animals treated with corn oil (CO), instead of carotenoid or retinoid, served as controls. At the end of the study, beta C treatment resulted in a substantial reduction in the hepatocyte nodule incidence, total number of nodules and in the nodule multiplicity, as well as in the number and size of hepatic gamma-glutamyltranspeptidase (gamma GT)-positive foci. In contrast, animals administered with VA presented a 100% nodule incidence and only a moderate decrease in the total number of hepatocyte nodules. These showed to be in the great majority larger than nodules observed after beta C treatment. Moreover, VA administration resulted in similar number and size of gamma GT-positive foci than controls. In addition, the hepatic concentrations of total VA increased in both, beta C and VA treated animals. However, as expected, increases in the hepatic carotenoid concentrations could be only observed after beta C application. Therefore, changes in the hepatic levels of beta C, and not of VA, resulted in appreciable inhibitory effects on preneoplastic lesions of the liver. The evidence implies that the chemopreventive property of beta C is unrelated to its provitamin A activity." @default.
- W2431053606 created "2016-06-24" @default.
- W2431053606 creator A5002696681 @default.
- W2431053606 creator A5037094399 @default.
- W2431053606 creator A5056423955 @default.
- W2431053606 creator A5057096936 @default.
- W2431053606 creator A5062688500 @default.
- W2431053606 creator A5069477694 @default.
- W2431053606 creator A5086818317 @default.
- W2431053606 date "1995-01-01" @default.
- W2431053606 modified "2023-09-23" @default.
- W2431053606 title "A comparison of beta-carotene and vitamin A effects on a hepatocarcinogenesis model." @default.
- W2431053606 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7591537" @default.
- W2431053606 hasPublicationYear "1995" @default.
- W2431053606 type Work @default.
- W2431053606 sameAs 2431053606 @default.
- W2431053606 citedByCount "7" @default.
- W2431053606 countsByYear W24310536062017 @default.
- W2431053606 countsByYear W24310536062019 @default.
- W2431053606 crossrefType "journal-article" @default.
- W2431053606 hasAuthorship W2431053606A5002696681 @default.
- W2431053606 hasAuthorship W2431053606A5037094399 @default.
- W2431053606 hasAuthorship W2431053606A5056423955 @default.
- W2431053606 hasAuthorship W2431053606A5057096936 @default.
- W2431053606 hasAuthorship W2431053606A5062688500 @default.
- W2431053606 hasAuthorship W2431053606A5069477694 @default.
- W2431053606 hasAuthorship W2431053606A5086818317 @default.
- W2431053606 hasConcept C126322002 @default.
- W2431053606 hasConcept C134018914 @default.
- W2431053606 hasConcept C151730666 @default.
- W2431053606 hasConcept C185592680 @default.
- W2431053606 hasConcept C199360897 @default.
- W2431053606 hasConcept C202751555 @default.
- W2431053606 hasConcept C2776174256 @default.
- W2431053606 hasConcept C2776200302 @default.
- W2431053606 hasConcept C2776731575 @default.
- W2431053606 hasConcept C2776940978 @default.
- W2431053606 hasConcept C2778206080 @default.
- W2431053606 hasConcept C2778859900 @default.
- W2431053606 hasConcept C2779573558 @default.
- W2431053606 hasConcept C41008148 @default.
- W2431053606 hasConcept C55493867 @default.
- W2431053606 hasConcept C71924100 @default.
- W2431053606 hasConcept C86803240 @default.
- W2431053606 hasConceptScore W2431053606C126322002 @default.
- W2431053606 hasConceptScore W2431053606C134018914 @default.
- W2431053606 hasConceptScore W2431053606C151730666 @default.
- W2431053606 hasConceptScore W2431053606C185592680 @default.
- W2431053606 hasConceptScore W2431053606C199360897 @default.
- W2431053606 hasConceptScore W2431053606C202751555 @default.
- W2431053606 hasConceptScore W2431053606C2776174256 @default.
- W2431053606 hasConceptScore W2431053606C2776200302 @default.
- W2431053606 hasConceptScore W2431053606C2776731575 @default.
- W2431053606 hasConceptScore W2431053606C2776940978 @default.
- W2431053606 hasConceptScore W2431053606C2778206080 @default.
- W2431053606 hasConceptScore W2431053606C2778859900 @default.
- W2431053606 hasConceptScore W2431053606C2779573558 @default.
- W2431053606 hasConceptScore W2431053606C41008148 @default.
- W2431053606 hasConceptScore W2431053606C55493867 @default.
- W2431053606 hasConceptScore W2431053606C71924100 @default.
- W2431053606 hasConceptScore W2431053606C86803240 @default.
- W2431053606 hasIssue "2" @default.
- W2431053606 hasLocation W24310536061 @default.
- W2431053606 hasOpenAccess W2431053606 @default.
- W2431053606 hasPrimaryLocation W24310536061 @default.
- W2431053606 hasRelatedWork W1581604820 @default.
- W2431053606 hasRelatedWork W1894439291 @default.
- W2431053606 hasRelatedWork W1986004033 @default.
- W2431053606 hasRelatedWork W2057538020 @default.
- W2431053606 hasRelatedWork W2060838475 @default.
- W2431053606 hasRelatedWork W211032082 @default.
- W2431053606 hasRelatedWork W2110972239 @default.
- W2431053606 hasRelatedWork W2111156724 @default.
- W2431053606 hasRelatedWork W2342210751 @default.
- W2431053606 hasRelatedWork W2431053606 @default.
- W2431053606 hasVolume "65" @default.
- W2431053606 isParatext "false" @default.
- W2431053606 isRetracted "false" @default.
- W2431053606 magId "2431053606" @default.
- W2431053606 workType "article" @default.