FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2431636503> ?p ?o ?g. }

• W2431636503 endingPage "675" @default.
• W2431636503 startingPage "657" @default.
• W2431636503 abstract "The critically ill surgical patient is at high risk for the development of ICU-acquired infection. Normal mucosal defenses are breached by surgical incisions or by intravascular devices, urinary catheters, and endotracheal tubes. The integrity of the gastrointestinal epithelium is compromised by the lack of enteral nutrition and episodes of hypoperfusion, resulting in translocation of normal or disturbed enteric flora. The indigenous microbial flora, an important component of normal host defenses against invasive infection, is disrupted through the use of broad-spectrum antibiotics or by poorly understood influences associated with critical illness. Systemic immunity is altered, and multiple abnormalities of specific and nonspecific immune function can be documented. Infections acquired within the ICU are commonly caused by endogenous organisms of low intrinsic pathogenicity, and the contribution of these infections to ICU outcome is controversial. Diagnosis is established by directed investigations, focusing on surgical sites and invasive devices. Therapy is primarily physical (drainage of infected collections or removal of contaminated devices), and antimicrobial therapy should employ narrow-spectrum agents guided by the results of Gram stain and culture. The prevention of ICU-acquired infection is based on timely and definitive surgical therapy, judicious use of invasive devices and antibiotics, and early enteral feeding. Infection-control measures aimed at endogenous reservoirs show some preliminary promise for certain subsets of patients, but remain, at present, experimental." @default.
• W2431636503 created "2016-06-24" @default.
• W2431636503 creator A5006701598 @default.
• W2431636503 creator A5023300205 @default.
• W2431636503 creator A5070604004 @default.
• W2431636503 date "1992-09-01" @default.
• W2431636503 modified "2023-09-27" @default.
• W2431636503 title "NOSOCOMIAL INFECTION IN THE SURGICAL INTENSIVE CARE UNIT" @default.
• W2431636503 cites W11373691 @default.
• W2431636503 cites W1480105763 @default.
• W2431636503 cites W1539177098 @default.
• W2431636503 cites W1907372042 @default.
• W2431636503 cites W1928909115 @default.
• W2431636503 cites W1951873137 @default.
• W2431636503 cites W1964088213 @default.
• W2431636503 cites W1964517457 @default.
• W2431636503 cites W1967950437 @default.
• W2431636503 cites W1972727943 @default.
• W2431636503 cites W1975489112 @default.
• W2431636503 cites W1976425934 @default.
• W2431636503 cites W1985757242 @default.
• W2431636503 cites W1986503852 @default.
• W2431636503 cites W1986506708 @default.
• W2431636503 cites W1987401363 @default.
• W2431636503 cites W1988524285 @default.
• W2431636503 cites W1991459115 @default.
• W2431636503 cites W1993933915 @default.
• W2431636503 cites W1994917617 @default.
• W2431636503 cites W1998189427 @default.
• W2431636503 cites W1999940957 @default.
• W2431636503 cites W2004298180 @default.
• W2431636503 cites W2010891658 @default.
• W2431636503 cites W2011291552 @default.
• W2431636503 cites W2022810183 @default.
• W2431636503 cites W2024631123 @default.
• W2431636503 cites W2029506989 @default.
• W2431636503 cites W2033744649 @default.
• W2431636503 cites W2033752286 @default.
• W2431636503 cites W2035873975 @default.
• W2431636503 cites W2041091557 @default.
• W2431636503 cites W2041286873 @default.
• W2431636503 cites W2044098758 @default.
• W2431636503 cites W2047320073 @default.
• W2431636503 cites W2058416598 @default.
• W2431636503 cites W2058626660 @default.
• W2431636503 cites W2062664728 @default.
• W2431636503 cites W2063516640 @default.
• W2431636503 cites W2063847223 @default.
• W2431636503 cites W2074887152 @default.
• W2431636503 cites W2075813177 @default.
• W2431636503 cites W2083058447 @default.
• W2431636503 cites W2086601789 @default.
• W2431636503 cites W2088165815 @default.
• W2431636503 cites W2091583949 @default.
• W2431636503 cites W2091649267 @default.
• W2431636503 cites W2091989722 @default.
• W2431636503 cites W2094946202 @default.
• W2431636503 cites W2100862733 @default.
• W2431636503 cites W2104734119 @default.
• W2431636503 cites W2106419536 @default.
• W2431636503 cites W2124571466 @default.
• W2431636503 cites W2134687787 @default.
• W2431636503 cites W2147122124 @default.
• W2431636503 cites W2152838260 @default.
• W2431636503 cites W2293384288 @default.
• W2431636503 cites W2313499625 @default.
• W2431636503 cites W2314608485 @default.
• W2431636503 cites W2332847148 @default.
• W2431636503 cites W2338283515 @default.
• W2431636503 cites W2407102458 @default.
• W2431636503 cites W2412526404 @default.
• W2431636503 cites W2417026960 @default.
• W2431636503 cites W2442059612 @default.
• W2431636503 cites W2583550038 @default.
• W2431636503 cites W2599527603 @default.
• W2431636503 cites W4241140431 @default.
• W2431636503 cites W1999399738 @default.
• W2431636503 cites W2059449310 @default.
• W2431636503 cites W2099385416 @default.
• W2431636503 cites W2104493016 @default.
• W2431636503 doi "https://doi.org/10.1016/s0891-5520(20)30468-2" @default.
• W2431636503 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1431044" @default.
• W2431636503 hasPublicationYear "1992" @default.
• W2431636503 type Work @default.
• W2431636503 sameAs 2431636503 @default.
• W2431636503 citedByCount "28" @default.
• W2431636503 countsByYear W24316365032017 @default.
• W2431636503 countsByYear W24316365032021 @default.
• W2431636503 crossrefType "journal-article" @default.
• W2431636503 hasAuthorship W2431636503A5006701598 @default.
• W2431636503 hasAuthorship W2431636503A5023300205 @default.
• W2431636503 hasAuthorship W2431636503A5070604004 @default.
• W2431636503 hasConcept C141071460 @default.
• W2431636503 hasConcept C166888038 @default.
• W2431636503 hasConcept C177713679 @default.
• W2431636503 hasConcept C203014093 @default.
• W2431636503 hasConcept C2776376669 @default.
• W2431636503 hasConcept C2776976047 @default.

• next