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- W2432401432 abstract "Background Mutations in the BRCA genes confer greater risk of developing breast, ovarian, and prostate cancer. Families carrying the mutation can have intensive surveillance and take preventative measures. This is the first report on the uptake of such interventions in Chinese mutation carriers residing in Asia. Methods Breast and ovarian cancer index patients and family members referred for genetic counselling and testing who are found to carry the BRCA mutations were included in this multicenter study. Results A total of 31 patients with breast and/or ovarian cancer were found to carry BRCA1 or BRCA2 mutations. Forty-one tested family members also carried the mutations. Of the females, 85.7% of the index patients opted for breast surveillance and 23.8% for prophylactic mastectomy. Of the family members, 82.4% chose breast surveillance and 17.7% had prophylactic mastectomy. The" @default.
- W2432401432 created "2016-06-24" @default.
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- W2432401432 creator A5068874466 @default.
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- W2432401432 date "2010-01-01" @default.
- W2432401432 modified "2023-09-27" @default.
- W2432401432 title "Choice of Management of Southern Chinese BRCA Mutation" @default.
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