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- W2432573191 abstract "Natural deep eutectic solvents (NADES) are combinations of two, or in a few cases three, common primary metabolites that form a liquid when mixed in a determined ratio in certain conditions (Dai et al., 2013a). Their components are mono or disaccharides, amino acids, simple organic acids (malic,lactic or citric acid) and other compounds such as choline chloride. The NADES have several advantages over other eutectic solvents or ionic liquids, being non-toxic, cheap and having all features of a “green solvent”. They have been proved to increase the solubility of a great variety of scarcely water-soluble compounds such as rutin, quercetin, cinnamic acid, taxol, carthamin, ginkgolide B aswell as the macromolecules gluten, DNA, and starch (Dai et al., 2013b, 2013c, 2014). There aredifferent types of NADES according to the nature of their components: acid, basic, neutral or ionicliquids. In this case, Narcissus pseudonarcissus alkaloids were extracted from dried bulb material with hot pressurized extraction using diverse NADES to compare their efficiency and selectivity. The main alkaloid in N.pseudonarcissus is galanthamine, an acetyl cholinesterase inhibitor that is used for thetreatment of Parkinson disease. This method is proposed as an alternative to its synthesis or acid extraction from diverse natural sources which are the current methods of industrial production." @default.
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- W2432573191 date "2014-01-01" @default.
- W2432573191 modified "2023-09-27" @default.
- W2432573191 title "EXTRACTION OF GALANTHAMINE FROM NARCISSUS BULBS USING NATURAL EUTECTIC SOLVENTS (NADES) AND HOT PRESSURIZED EXTRACTION (HPE)" @default.
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