Matches in SemOpenAlex for { <https://semopenalex.org/work/W2433380805> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2433380805 endingPage "9" @default.
- W2433380805 startingPage "84" @default.
- W2433380805 abstract "The results of 12 weeks treatment of primary hyperlipidemias with Lovastatin are presented. This drug belonging to a new generation of hypercholesterolemic drugs inhibits the endogenous synthesis of cholesterol by means of inhibiting the HMG-CoA reductase. The sample consisted of 30 men aged 28-68 years: in 17 of them heterozygotic familial hypercholesterolemia (FH) was diagnosed and in 13--primary non familial hypercholesterolemia (NFH). After 12 weeks of treatment in both groups a significant reduction of total serum cholesterol concentration was observed--(-28%) and--(-32%) as well as LDL-cholesterol concentration (in both groups about -37%) and apo B concentration--(-32%) and -34%. Only in one patients with NFH a significant reduction of VLDL-cholesterol (-29%) and or triglycerides (-15%) concentrations was observed. In this group also a 9% increase of HLD-cholesterol, mainly HDL-2 concentration, was found. Side effects were observed in 6 patients--in 4 of them a minor increase of ALAT, AsPAT or CPK activities (less than 3 times above norm were observed) without any symptoms and with a spontaneous normalization with no need to stop treatment, and in 2 of them abdominal pains not causing drug treatment cessation." @default.
- W2433380805 created "2016-06-24" @default.
- W2433380805 creator A5016115106 @default.
- W2433380805 creator A5044065092 @default.
- W2433380805 creator A5053826334 @default.
- W2433380805 creator A5055037134 @default.
- W2433380805 creator A5071008903 @default.
- W2433380805 creator A5087561425 @default.
- W2433380805 date "1991-01-01" @default.
- W2433380805 modified "2023-09-25" @default.
- W2433380805 title "[Lovastatin in the treatment of primary hypercholesterolemia]." @default.
- W2433380805 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1942761" @default.
- W2433380805 hasPublicationYear "1991" @default.
- W2433380805 type Work @default.
- W2433380805 sameAs 2433380805 @default.
- W2433380805 citedByCount "0" @default.
- W2433380805 crossrefType "journal-article" @default.
- W2433380805 hasAuthorship W2433380805A5016115106 @default.
- W2433380805 hasAuthorship W2433380805A5044065092 @default.
- W2433380805 hasAuthorship W2433380805A5053826334 @default.
- W2433380805 hasAuthorship W2433380805A5055037134 @default.
- W2433380805 hasAuthorship W2433380805A5071008903 @default.
- W2433380805 hasAuthorship W2433380805A5087561425 @default.
- W2433380805 hasConcept C104950815 @default.
- W2433380805 hasConcept C126322002 @default.
- W2433380805 hasConcept C134018914 @default.
- W2433380805 hasConcept C134651460 @default.
- W2433380805 hasConcept C181199279 @default.
- W2433380805 hasConcept C185592680 @default.
- W2433380805 hasConcept C2778163477 @default.
- W2433380805 hasConcept C2779091943 @default.
- W2433380805 hasConcept C2779120738 @default.
- W2433380805 hasConcept C2780035454 @default.
- W2433380805 hasConcept C2780940807 @default.
- W2433380805 hasConcept C55493867 @default.
- W2433380805 hasConcept C555293320 @default.
- W2433380805 hasConcept C71924100 @default.
- W2433380805 hasConcept C90924648 @default.
- W2433380805 hasConcept C98274493 @default.
- W2433380805 hasConceptScore W2433380805C104950815 @default.
- W2433380805 hasConceptScore W2433380805C126322002 @default.
- W2433380805 hasConceptScore W2433380805C134018914 @default.
- W2433380805 hasConceptScore W2433380805C134651460 @default.
- W2433380805 hasConceptScore W2433380805C181199279 @default.
- W2433380805 hasConceptScore W2433380805C185592680 @default.
- W2433380805 hasConceptScore W2433380805C2778163477 @default.
- W2433380805 hasConceptScore W2433380805C2779091943 @default.
- W2433380805 hasConceptScore W2433380805C2779120738 @default.
- W2433380805 hasConceptScore W2433380805C2780035454 @default.
- W2433380805 hasConceptScore W2433380805C2780940807 @default.
- W2433380805 hasConceptScore W2433380805C55493867 @default.
- W2433380805 hasConceptScore W2433380805C555293320 @default.
- W2433380805 hasConceptScore W2433380805C71924100 @default.
- W2433380805 hasConceptScore W2433380805C90924648 @default.
- W2433380805 hasConceptScore W2433380805C98274493 @default.
- W2433380805 hasIssue "8" @default.
- W2433380805 hasLocation W24333808051 @default.
- W2433380805 hasOpenAccess W2433380805 @default.
- W2433380805 hasPrimaryLocation W24333808051 @default.
- W2433380805 hasRelatedWork W1964382916 @default.
- W2433380805 hasRelatedWork W2049939222 @default.
- W2433380805 hasRelatedWork W2055281491 @default.
- W2433380805 hasRelatedWork W2111344667 @default.
- W2433380805 hasRelatedWork W2128813931 @default.
- W2433380805 hasRelatedWork W2181892563 @default.
- W2433380805 hasRelatedWork W2409334172 @default.
- W2433380805 hasRelatedWork W2432383190 @default.
- W2433380805 hasRelatedWork W2433380805 @default.
- W2433380805 hasRelatedWork W3145156464 @default.
- W2433380805 hasVolume "35" @default.
- W2433380805 isParatext "false" @default.
- W2433380805 isRetracted "false" @default.
- W2433380805 magId "2433380805" @default.
- W2433380805 workType "article" @default.