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- W2433406339 abstract "The expression of p53 protein was examined in a series of 69 children with acute lymphoblastic leukemia with two different monoclonal antibodies (Mab 1801 and 240). p53 expression was detected with at least one antibody in 49 cases (71%), whereas only 19 cases (27%) were positive with both antibodies. Variability in the immunostaining could be observed depending on the antibody used. Mab 240 gave the highest rate of positive staining (58%), followed by 1801 with 39%. Positive staining with 1801 was significantly associated with decreased proliferation of tumor cells as measured by Ki-67 labelling, indicating that possibly the wild-type p53 protein is preferably stained with this antibody. However, neither of the two antibodies has prognostic value or is correlated with histopathological parameters." @default.
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- W2433406339 date "1995-05-01" @default.
- W2433406339 modified "2023-09-23" @default.
- W2433406339 title "p53 protein detected by two different antibodies: relationship to proliferation and prognosis in acute lymphoblastic leukemia." @default.
- W2433406339 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7645923" @default.
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