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• W2433503705 startingPage "434" @default.
• W2433503705 abstract "The clinical presentation of infants with critical aortic stenosis, as well as the results of surgical treatment, differs from obstruction of the left ventricular outflow tract in older children. To investigate a possible anatomic basis for this situation, we performed a detailed morphometric study of 21 hearts from infants who had critical aortic stenosis and 11 normal hearts from infants less than 3 months of age. In each of the hearts with critical aortic stenosis, only one commissure extended to the sinutubular ridge. The other two commissures were represented by folds in the aortic wall that suspended the leaflet below the level of the sinutubular junction. The leaflet thus had a free edge shorter than the circumference of the sinus, in contrast with the normal valve, in which leaflets always were longer than the circumference of their supporting sinus. Analysis of the fibrous triangles on the ventricular aspect of abnormal valves showed a symmetric three-sinus arrangement. In all but one specimen, however, only the triangle related to the mitral valve was fully developed. Although incision of both rudimentary commissures to the aortic wall should achieve some relief of obstruction, these morphologic features strongly mitigate against surgical restoration of normal function or growth in aortic valves having the morphology observed in this series of hearts." @default.
• W2433503705 created "2016-06-24" @default.
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• W2433503705 date "1992-08-01" @default.
• W2433503705 modified "2023-10-17" @default.
• W2433503705 title "Morphology of the ventriculoaortic junction in critical aortic stenosis. Implications for hemodynamic function and clinical management." @default.
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• W2433503705 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1495307" @default.
• W2433503705 hasPublicationYear "1992" @default.
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