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- W2433952005 abstract "A review of literature data reveals that for the last years, the molecular biology techniques have been of an increasing use in the study of the Escherichia coli genome, having supplemented the standard genetic mapping. For the proper understanding of the Escherichia coli genome organization, recombinational events occurring in the course of evolution should be considered. The bacterial genome seems to carry traces of both long-term evolution, possibly responsible for appearance of the bacterial cell itself, and current evolution, consisting mainly of periodic genome entering by new plasmid-originated genes. It is supposed that in the process of stabilization within a genome, every new gene undergoes a stage of the transgene, that is the gene situated in a transposon on the chromosome. In parallel with integration of new genes into the genome, some genes deleting should also take place. The formation of deletions could occur by unequal crossing over in segments of direct homologous repeats which seem to be ordinarily revealed in the experimental study of the tandem gene duplications." @default.
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- W2433952005 date "1985-05-01" @default.
- W2433952005 modified "2023-09-23" @default.
- W2433952005 title "[Organization of the Escherichia coli genome]." @default.
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