Matches in SemOpenAlex for { <https://semopenalex.org/work/W2433965798> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2433965798 endingPage "4" @default.
- W2433965798 startingPage "393" @default.
- W2433965798 abstract "In this study we compared the circulatory effects of the arginine analogue non-specific nitric oxide synthase (NOS) inhibitor N omega-nitro-L-arginine (NNA), and the specific inducible NOS (iNOS) inhibitor S-methylisothiourea (SMT) and S-(2-aminoethyl)-isothiourea (AEST) in a hyperdynamic endotoxemic dog model. Mean arterial pressure (MAP), cardiac output (CO), and myocardial contractility (MC) were measured. A hyperdynamic circulatory response was elicited with a 2-h infusion of a total dose of 5.3 micrograms/kg E. coli endotoxin (ETX). NOS inhibitory treatment (2 mg/kg) was administrated from the 45th min of endotoxemia. ETX induced a hyperdynamic circulatory response, and a significant myocardial depression. NNA induced a prolonged, SMT a transient increase in MC, both drugs elevated MAP, but decreased CO. AEST significantly prolonged the elevation in CO, but did not affect MAP. Selective inhibition of the iNOS may be a beneficial in sepsis." @default.
- W2433965798 created "2016-06-24" @default.
- W2433965798 creator A5018021794 @default.
- W2433965798 creator A5025345646 @default.
- W2433965798 creator A5027268238 @default.
- W2433965798 creator A5049775704 @default.
- W2433965798 creator A5058049602 @default.
- W2433965798 date "1997-01-01" @default.
- W2433965798 modified "2023-09-26" @default.
- W2433965798 title "Effects of nitric oxide synthase inhibition on the hemodynamic changes in hyperdynamic endotoxemia." @default.
- W2433965798 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9408415" @default.
- W2433965798 hasPublicationYear "1997" @default.
- W2433965798 type Work @default.
- W2433965798 sameAs 2433965798 @default.
- W2433965798 citedByCount "0" @default.
- W2433965798 crossrefType "journal-article" @default.
- W2433965798 hasAuthorship W2433965798A5018021794 @default.
- W2433965798 hasAuthorship W2433965798A5025345646 @default.
- W2433965798 hasAuthorship W2433965798A5027268238 @default.
- W2433965798 hasAuthorship W2433965798A5049775704 @default.
- W2433965798 hasAuthorship W2433965798A5058049602 @default.
- W2433965798 hasConcept C126322002 @default.
- W2433965798 hasConcept C139940330 @default.
- W2433965798 hasConcept C178853913 @default.
- W2433965798 hasConcept C2776452961 @default.
- W2433965798 hasConcept C2777622882 @default.
- W2433965798 hasConcept C2777953023 @default.
- W2433965798 hasConcept C2778384902 @default.
- W2433965798 hasConcept C39133596 @default.
- W2433965798 hasConcept C42219234 @default.
- W2433965798 hasConcept C519581460 @default.
- W2433965798 hasConcept C71924100 @default.
- W2433965798 hasConcept C72859922 @default.
- W2433965798 hasConcept C84393581 @default.
- W2433965798 hasConcept C98274493 @default.
- W2433965798 hasConceptScore W2433965798C126322002 @default.
- W2433965798 hasConceptScore W2433965798C139940330 @default.
- W2433965798 hasConceptScore W2433965798C178853913 @default.
- W2433965798 hasConceptScore W2433965798C2776452961 @default.
- W2433965798 hasConceptScore W2433965798C2777622882 @default.
- W2433965798 hasConceptScore W2433965798C2777953023 @default.
- W2433965798 hasConceptScore W2433965798C2778384902 @default.
- W2433965798 hasConceptScore W2433965798C39133596 @default.
- W2433965798 hasConceptScore W2433965798C42219234 @default.
- W2433965798 hasConceptScore W2433965798C519581460 @default.
- W2433965798 hasConceptScore W2433965798C71924100 @default.
- W2433965798 hasConceptScore W2433965798C72859922 @default.
- W2433965798 hasConceptScore W2433965798C84393581 @default.
- W2433965798 hasConceptScore W2433965798C98274493 @default.
- W2433965798 hasIssue "1-4" @default.
- W2433965798 hasLocation W24339657981 @default.
- W2433965798 hasOpenAccess W2433965798 @default.
- W2433965798 hasPrimaryLocation W24339657981 @default.
- W2433965798 hasRelatedWork W169209435 @default.
- W2433965798 hasRelatedWork W1980018179 @default.
- W2433965798 hasRelatedWork W1996610578 @default.
- W2433965798 hasRelatedWork W2022157344 @default.
- W2433965798 hasRelatedWork W2061579801 @default.
- W2433965798 hasRelatedWork W2063880047 @default.
- W2433965798 hasRelatedWork W2107714191 @default.
- W2433965798 hasRelatedWork W2398026541 @default.
- W2433965798 hasRelatedWork W2413503736 @default.
- W2433965798 hasRelatedWork W2433965798 @default.
- W2433965798 hasVolume "36" @default.
- W2433965798 isParatext "false" @default.
- W2433965798 isRetracted "false" @default.
- W2433965798 magId "2433965798" @default.
- W2433965798 workType "article" @default.