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• W2434175965 abstract "13α-Estrone derivatives containing various substituents on C-3 and C-17 were synthesized, and evaluated by means of MTT assays for in vitro antiproliferative activity against a panel of human adherent cancer cell lines (HeLa, MCF-7, A2780 and A431). Compounds with N-benzyltriazolylmethoxy moieties on C-3 proved to be more potent than their 3-hydroxy or 3-ether counterparts. Some triazoles exerted substantial cytostatic effects against particular tumor cell lines, with submicromolar IC50 values." @default.
• W2434175965 created "2016-06-24" @default.
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• W2434175965 date "2016-09-01" @default.
• W2434175965 modified "2023-10-17" @default.
• W2434175965 title "Synthesis and biological evaluation of 13α-estrone derivatives as potential antiproliferative agents" @default.
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• W2434175965 doi "https://doi.org/10.1016/j.steroids.2016.05.010" @default.
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