FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W24343577> ?p ?o ?g. }

• W24343577 endingPage "43" @default.
• W24343577 startingPage "335" @default.
• W24343577 abstract "The elastic properties of 22 common carotid arteries from 13 male cynomolgus monkeys (M. fascicularis) that were fed either a high cholesterol (test) diet or a standard monkey chow (control) diet for 18 months were measured noninvasively with 5 MHz ultrasound. A B-mode image of the artery was obtained with a 32-element linear array transducer, and a single line of video ultrasonic information was selected for tracking the echoes from the adventitial side of the near wall to the lumen-intima interface of the far wall. This technique measured lumen diameter plus anterior wall thickness. The diastolic diameter (Dd) (mean +/- SEM) of the test arteries was slightly larger than controls (2.9 +/- 0.1 vs 2.5 +/- 0.1 mm), whereas the fractional diameter change from diastole to systole (DeltaD/Dd, where DeltaD = diameter change) was slightly less (0.062 +/- 0.010 vs 0.082 +/- 0.011). Direct subclavian artery pulse pressure (DeltaP) in the test animals (63 +/- 4 mm Hg) was significantly greater than in the controls (41 +/- 2 mm Hg), whereas there was no difference in diastolic pressure (85 +/- 3 vs 81 +/- 2), respectively. The pressure-strain elastic modulus Ep = (DeltaP/DeltaD) Dd was significantly greater in the test monkeys (182 +/- 33 kPa) than in the controls (73 +/- 9 kPa). Morphometric analysis of atherosclerosis revealed more connective tissue and intra- and extracellular lipids in the test arteries than in the controls. Based on the average of three cross-sections equally spaced along each common carotid artery, the intimal area and the maximal intimal thickness averaged 0.89 +/- 0.16 mm2 and 0.26 +/- 0.04 mm for the test monkeys compared to negligible intimae from the controls. Medial area also was significantly greater in the test monkeys (0.71 +/- 0.03 mm2) compared to controls (0.57 +/- 0.04 mm2). Percentage stenosis defined as intimal area/IEL area, where IEL area is that within the internal elastic lamina, showed the test arteries to have 30 +/- 5% stenosis compared to 0% for the controls. However, dilatation appeared to compensate for any loss in lumen area due to intimal thickening. In this study, significant carotid artery stiffening associated with diet-induced atherosclerosis is demonstrated. This noninvasive technique may be useful in pediatrics and in preventive medicine for the detection of arterial stiffening associated with early progressive atherosclerotic lesions." @default.
• W24343577 created "2016-06-24" @default.
• W24343577 creator A5011285644 @default.
• W24343577 creator A5020590606 @default.
• W24343577 creator A5046338726 @default.
• W24343577 creator A5062899391 @default.
• W24343577 creator A5064766873 @default.
• W24343577 date "1982-09-01" @default.
• W24343577 modified "2023-09-24" @default.
• W24343577 title "Detection of early atherosclerosis in M. fascicularis with transcutaneous ultrasonic measurement of the elastic properties of the common carotid artery." @default.
• W24343577 cites W1968179320 @default.
• W24343577 cites W1985652174 @default.
• W24343577 cites W1987575301 @default.
• W24343577 cites W2065834320 @default.
• W24343577 cites W2077324295 @default.
• W24343577 cites W2090633706 @default.
• W24343577 cites W2120892882 @default.
• W24343577 cites W2152280099 @default.
• W24343577 cites W2409047955 @default.
• W24343577 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/351640" @default.
• W24343577 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15226937" @default.
• W24343577 hasPublicationYear "1982" @default.
• W24343577 type Work @default.
• W24343577 sameAs 24343577 @default.
• W24343577 citedByCount "3" @default.
• W24343577 crossrefType "journal-article" @default.
• W24343577 hasAuthorship W24343577A5011285644 @default.
• W24343577 hasAuthorship W24343577A5020590606 @default.
• W24343577 hasAuthorship W24343577A5046338726 @default.
• W24343577 hasAuthorship W24343577A5062899391 @default.
• W24343577 hasAuthorship W24343577A5064766873 @default.
• W24343577 hasConcept C105702510 @default.
• W24343577 hasConcept C126322002 @default.
• W24343577 hasConcept C126838900 @default.
• W24343577 hasConcept C131631996 @default.
• W24343577 hasConcept C136229726 @default.
• W24343577 hasConcept C142724271 @default.
• W24343577 hasConcept C143753070 @default.
• W24343577 hasConcept C164705383 @default.
• W24343577 hasConcept C169554166 @default.
• W24343577 hasConcept C17140001 @default.
• W24343577 hasConcept C2776820930 @default.
• W24343577 hasConcept C2779318932 @default.
• W24343577 hasConcept C2781064879 @default.
• W24343577 hasConcept C2987047532 @default.
• W24343577 hasConcept C518705261 @default.
• W24343577 hasConcept C57900726 @default.
• W24343577 hasConcept C71924100 @default.
• W24343577 hasConcept C81288441 @default.
• W24343577 hasConcept C84393581 @default.
• W24343577 hasConceptScore W24343577C105702510 @default.
• W24343577 hasConceptScore W24343577C126322002 @default.
• W24343577 hasConceptScore W24343577C126838900 @default.
• W24343577 hasConceptScore W24343577C131631996 @default.
• W24343577 hasConceptScore W24343577C136229726 @default.
• W24343577 hasConceptScore W24343577C142724271 @default.
• W24343577 hasConceptScore W24343577C143753070 @default.
• W24343577 hasConceptScore W24343577C164705383 @default.
• W24343577 hasConceptScore W24343577C169554166 @default.
• W24343577 hasConceptScore W24343577C17140001 @default.
• W24343577 hasConceptScore W24343577C2776820930 @default.
• W24343577 hasConceptScore W24343577C2779318932 @default.
• W24343577 hasConceptScore W24343577C2781064879 @default.
• W24343577 hasConceptScore W24343577C2987047532 @default.
• W24343577 hasConceptScore W24343577C518705261 @default.
• W24343577 hasConceptScore W24343577C57900726 @default.
• W24343577 hasConceptScore W24343577C71924100 @default.
• W24343577 hasConceptScore W24343577C81288441 @default.
• W24343577 hasConceptScore W24343577C84393581 @default.
• W24343577 hasIssue "3" @default.
• W24343577 hasLocation W243435771 @default.
• W24343577 hasOpenAccess W24343577 @default.
• W24343577 hasPrimaryLocation W243435771 @default.
• W24343577 hasRelatedWork W149080032 @default.
• W24343577 hasRelatedWork W1497564180 @default.
• W24343577 hasRelatedWork W1966356572 @default.
• W24343577 hasRelatedWork W2001143991 @default.
• W24343577 hasRelatedWork W2019931817 @default.
• W24343577 hasRelatedWork W2066720643 @default.
• W24343577 hasRelatedWork W2099501302 @default.
• W24343577 hasRelatedWork W2102696371 @default.
• W24343577 hasRelatedWork W2107554306 @default.
• W24343577 hasRelatedWork W2124582458 @default.
• W24343577 hasRelatedWork W2128038321 @default.
• W24343577 hasRelatedWork W2137173696 @default.
• W24343577 hasRelatedWork W2145601797 @default.
• W24343577 hasRelatedWork W2147824502 @default.
• W24343577 hasRelatedWork W2352681886 @default.
• W24343577 hasRelatedWork W2373723276 @default.
• W24343577 hasRelatedWork W2373735131 @default.
• W24343577 hasRelatedWork W2409327351 @default.
• W24343577 hasRelatedWork W2419204268 @default.
• W24343577 hasRelatedWork W3145582412 @default.
• W24343577 hasVolume "9" @default.
• W24343577 isParatext "false" @default.
• W24343577 isRetracted "false" @default.
• W24343577 magId "24343577" @default.
• W24343577 workType "article" @default.