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• W2434606567 abstract "Ribonuclease H (RNase H), first observed in extracts of calf thymus, is an apparently ubiquitous enzyme activity (1), which catalyzes the hydrolysis of RNA in RNA-DNA heteroduplexes (2). The two main classes (Type I and II) of eukaryotic RNase H have different biochemical requirements for maximal activity. A nuclear localization has been proposed (3,4), although different subnuclear fractions for the separate types have been suggested (see ref. 5). The proposed physiological roles, DNA duplication (class I), and RNA replication (class II), are both nuclear processes (see refs. 5 and 6)." @default.
• W2434606567 created "2016-06-24" @default.
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• W2434606567 date "2003-11-14" @default.
• W2434606567 modified "2023-09-24" @default.
• W2434606567 title "The Direction of Ribonucleases H by Antisense Oligodeoxynucleotides" @default.
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• W2434606567 doi "https://doi.org/10.1385/1-59259-233-3:157" @default.
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