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- W2435351421 abstract "Repeated subcutaneous administration of benzene to rabbits (0.25 or 0.5 ml/kg/day) produced a progressive lymphocytopenia with a 80% reduction in total circulating lymphocytes after 10 days of treatment. This decrease in circulating lymphocytes was due primarily to a reduction in B- cells with 17-30% remaining after 10 days of treatment, depending on the dose. Immunoglobin surface receptor - negative cells, presumably T lymphocytes, were relatively unaffected until late in the experiment at the high dose. It is concluded that benzene has a relatively selective cytotoxic effect on circulating B-lymphocytes in the rabbit." @default.
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- W2435351421 date "1980-01-01" @default.
- W2435351421 modified "2023-09-23" @default.
- W2435351421 title "Effect of short term benzene administration on circulating lymphocyte subpopulations in the rabbit: evidence of a selective B-lymphocyte sensitivity." @default.
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