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- W2435663279 abstract "Dietary modifications have been shown to contribute to the physical and mental diseases. Oxidative modifications of protein can be easily found in protein-rich food such as meat and milk products. Previous studies mainly focus on the consequences of lipid oxidation products intake in vivo, but the effects of protein oxidation products consumption have been largely neglected. Oxidants have been shown to play an important role in aging and neurodegenerative diseases. Dityrosine is the oxidated product of tyrosine residues in protein which is considered as a biomarker for oxidative stress, but the potential deleterious effects of dityrosine are unknown. In the present study, we explored the effects of dityrosine administration on the behavioral aspect. We found that dityrosine-ingested mice displayed impaired memory during novel object recognition test, but no influence to the spatial memory in Morris water maze compared with the saline group. Other aspects of neurobehavioral function such as locomotor activity, anxiety and social behavior were not affected by dityrosine ingestion. Furthermore, we found that dityrosine-ingested mice showed decreased expression level of NMDA receptor subunits Nr1, Nr2a, Nr2b as well as Bdnf, Trkb. Our study suggests that dityrosine exposure impairs hippocampus-dependent nonspatial memory accompanied by modulation of NMDA receptor subunits and Bdnf expression." @default.
- W2435663279 created "2016-06-24" @default.
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- W2435663279 date "2016-10-01" @default.
- W2435663279 modified "2023-10-17" @default.
- W2435663279 title "Dityrosine administration induces novel object recognition deficits in young adulthood mice" @default.
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- W2435663279 cites W1969699111 @default.
- W2435663279 cites W1980357013 @default.
- W2435663279 cites W1984775161 @default.
- W2435663279 cites W1985940694 @default.
- W2435663279 cites W1986503634 @default.
- W2435663279 cites W1986568367 @default.
- W2435663279 cites W1988295674 @default.
- W2435663279 cites W1996177596 @default.
- W2435663279 cites W1996860397 @default.
- W2435663279 cites W1999042659 @default.
- W2435663279 cites W1999151633 @default.
- W2435663279 cites W2001705739 @default.
- W2435663279 cites W2003630580 @default.
- W2435663279 cites W2007505601 @default.
- W2435663279 cites W2008520208 @default.
- W2435663279 cites W2012482368 @default.
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- W2435663279 cites W2035228750 @default.
- W2435663279 cites W2036670015 @default.
- W2435663279 cites W2037323275 @default.
- W2435663279 cites W2037376820 @default.
- W2435663279 cites W2045007926 @default.
- W2435663279 cites W2046922635 @default.
- W2435663279 cites W2047731623 @default.
- W2435663279 cites W2047777256 @default.
- W2435663279 cites W2048560630 @default.
- W2435663279 cites W2053933829 @default.
- W2435663279 cites W2057286178 @default.
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- W2435663279 cites W2058441068 @default.
- W2435663279 cites W2063142823 @default.
- W2435663279 cites W2068215666 @default.
- W2435663279 cites W2069028832 @default.
- W2435663279 cites W2072441360 @default.
- W2435663279 cites W2074198675 @default.
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- W2435663279 doi "https://doi.org/10.1016/j.physbeh.2016.06.019" @default.
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