FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2435846517> ?p ?o ?g. }

• W2435846517 endingPage "19" @default.
• W2435846517 startingPage "19" @default.
• W2435846517 abstract "Several angiogenic factors are involved in the development and progression of hepatocellular carcinoma (HCC), a hypervascular tumor. Vascular endothelial growth factor (VEGF) is a primary driving force for angiogenesis, and its overexpression has been reported in HCC. However, the significance of plasma and tissue VEGF levels in HCC in Egyptian patients with chronic hepatitis C (CHC) infection is understudied. The aim of this study was to evaluate the role of VEGF (measured in plasma and liver tissue) in patients with hepatitis C virus-related HCC and to assess its significance in the diagnosis and prognosis of HCC.A total of 90 subjects were studied. Among 90 subjects, 60 with CHC were examined and were subdivided into two groups: 30 patients with CHC-related HCC (HCC group) and 30 patients with CHC without HCC (non-HCC group). Thirty apparently healthy subjects served as the control group. VEGF was estimated in plasma by enzyme-linked immunosorbent assay and its expression in liver tissue was evaluated by real-time polymerase chain reaction. VEGF expression level and its relationship to tumor parameters, patients' liver function profile, and patients' clinical parameters were also investigated.Plasma VEGF levels in the HCC group were significantly higher than those of the non-HCC group, and both groups had significantly higher plasma VEGF levels than did the control group. Liver tissue VEGF expression was significantly higher in the HCC group than in the non-HCC group and positively correlated with plasma VEGF in the HCC group. The plasma VEGF levels were positively correlated with patients' age, aspartate aminotransferase levels, serum alpha-fetoprotein levels, the presence of portal vein thrombosis, and the number of hepatic focal lesions in the HCC group. However, plasma VEGF levels were not significantly correlated with the Child-Pugh score, alanine aminotransferase levels, the size of focal lesions, and Okuda stage. Using both the VEGF and alpha-fetoprotein levels to detect HCC maximizes the sensitivity and specificity.Plasma levels of VEGF may be a useful diagnostic and prognostic marker for HCC in patients who have been diagnosed with CHC." @default.
• W2435846517 created "2016-06-24" @default.
• W2435846517 creator A5008642671 @default.
• W2435846517 creator A5046065062 @default.
• W2435846517 creator A5072534258 @default.
• W2435846517 creator A5081952883 @default.
• W2435846517 creator A5087216338 @default.
• W2435846517 creator A5090830648 @default.
• W2435846517 creator A5091812757 @default.
• W2435846517 date "2016-06-01" @default.
• W2435846517 modified "2023-09-26" @default.
• W2435846517 title "Clinical significance of vascular endothelial growth factor in hepatitis C related hepatocellular carcinoma in Egyptian patients" @default.
• W2435846517 cites W109317992 @default.
• W2435846517 cites W129437821 @default.
• W2435846517 cites W1573207765 @default.
• W2435846517 cites W1981989535 @default.
• W2435846517 cites W1982877508 @default.
• W2435846517 cites W1996703005 @default.
• W2435846517 cites W2021805276 @default.
• W2435846517 cites W2028850957 @default.
• W2435846517 cites W2028978611 @default.
• W2435846517 cites W2034819626 @default.
• W2435846517 cites W2047165004 @default.
• W2435846517 cites W2059650257 @default.
• W2435846517 cites W2060123467 @default.
• W2435846517 cites W2079464218 @default.
• W2435846517 cites W2080992186 @default.
• W2435846517 cites W2084155816 @default.
• W2435846517 cites W2084650284 @default.
• W2435846517 cites W2094174828 @default.
• W2435846517 cites W2102942095 @default.
• W2435846517 cites W2106787323 @default.
• W2435846517 cites W2131378465 @default.
• W2435846517 cites W2138407594 @default.
• W2435846517 cites W2140396673 @default.
• W2435846517 cites W2171932951 @default.
• W2435846517 cites W2298877997 @default.
• W2435846517 cites W2337322841 @default.
• W2435846517 cites W2410470909 @default.
• W2435846517 cites W2415622717 @default.
• W2435846517 cites W2591717879 @default.
• W2435846517 cites W2615310051 @default.
• W2435846517 cites W35511592 @default.
• W2435846517 cites W72148400 @default.
• W2435846517 doi "https://doi.org/10.2147/jhc.s86708" @default.
• W2435846517 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4994801" @default.
• W2435846517 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27574588" @default.
• W2435846517 hasPublicationYear "2016" @default.
• W2435846517 type Work @default.
• W2435846517 sameAs 2435846517 @default.
• W2435846517 citedByCount "12" @default.
• W2435846517 countsByYear W24358465172017 @default.
• W2435846517 countsByYear W24358465172018 @default.
• W2435846517 countsByYear W24358465172019 @default.
• W2435846517 countsByYear W24358465172020 @default.
• W2435846517 countsByYear W24358465172021 @default.
• W2435846517 countsByYear W24358465172022 @default.
• W2435846517 countsByYear W24358465172023 @default.
• W2435846517 crossrefType "journal-article" @default.
• W2435846517 hasAuthorship W2435846517A5008642671 @default.
• W2435846517 hasAuthorship W2435846517A5046065062 @default.
• W2435846517 hasAuthorship W2435846517A5072534258 @default.
• W2435846517 hasAuthorship W2435846517A5081952883 @default.
• W2435846517 hasAuthorship W2435846517A5087216338 @default.
• W2435846517 hasAuthorship W2435846517A5090830648 @default.
• W2435846517 hasAuthorship W2435846517A5091812757 @default.
• W2435846517 hasBestOaLocation W24358465171 @default.
• W2435846517 hasConcept C126322002 @default.
• W2435846517 hasConcept C142724271 @default.
• W2435846517 hasConcept C143998085 @default.
• W2435846517 hasConcept C167734588 @default.
• W2435846517 hasConcept C203014093 @default.
• W2435846517 hasConcept C2522874641 @default.
• W2435846517 hasConcept C2776408679 @default.
• W2435846517 hasConcept C2776455275 @default.
• W2435846517 hasConcept C2777025900 @default.
• W2435846517 hasConcept C2778019345 @default.
• W2435846517 hasConcept C2780394083 @default.
• W2435846517 hasConcept C2992208098 @default.
• W2435846517 hasConcept C63363279 @default.
• W2435846517 hasConcept C71924100 @default.
• W2435846517 hasConcept C90924648 @default.
• W2435846517 hasConceptScore W2435846517C126322002 @default.
• W2435846517 hasConceptScore W2435846517C142724271 @default.
• W2435846517 hasConceptScore W2435846517C143998085 @default.
• W2435846517 hasConceptScore W2435846517C167734588 @default.
• W2435846517 hasConceptScore W2435846517C203014093 @default.
• W2435846517 hasConceptScore W2435846517C2522874641 @default.
• W2435846517 hasConceptScore W2435846517C2776408679 @default.
• W2435846517 hasConceptScore W2435846517C2776455275 @default.
• W2435846517 hasConceptScore W2435846517C2777025900 @default.
• W2435846517 hasConceptScore W2435846517C2778019345 @default.
• W2435846517 hasConceptScore W2435846517C2780394083 @default.
• W2435846517 hasConceptScore W2435846517C2992208098 @default.
• W2435846517 hasConceptScore W2435846517C63363279 @default.
• W2435846517 hasConceptScore W2435846517C71924100 @default.
• W2435846517 hasConceptScore W2435846517C90924648 @default.
• W2435846517 hasLocation W24358465171 @default.

• next