Matches in SemOpenAlex for { <https://semopenalex.org/work/W2435960278> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2435960278 endingPage "9" @default.
- W2435960278 startingPage "62" @default.
- W2435960278 abstract "The effects of the antitumor drug tiazofurin on development of sea urchins Sphaerechinus granularis, Paracentrotus lividus, Strongylocentrotus intermedius, and Arbacia lixula were studied. When 0.01-200 microM tiazofurin (TAF) was introduced in the incubation medium (artificial sea water) just after fertilization or at the midblastula stage, the development proceeded quite normally until the beginning of gastrulation. But later TAF blocked gastrulation and induced formation of mobile ball-shaped larvae with normal pigment cells but devoid of the nervous system, skeletal spicules and digestive tract. The threshold TAF concentrations varied from 0.05 microM (S. granularis) to 2-5 microM (all other species). When TAF was introduced during gastrulation and just after gastrulation, the larvae had defective nervous system and skeleton and suppressed expression of gangliosides. The nonhydrolyzable analog of GTP, GTP-gamma-S (5-20 microM), introduced in artificial sea water no later than at the midblastula stage prevented all above mentioned developmental defects." @default.
- W2435960278 created "2016-06-24" @default.
- W2435960278 creator A5013379343 @default.
- W2435960278 creator A5020843244 @default.
- W2435960278 creator A5035161884 @default.
- W2435960278 creator A5040493655 @default.
- W2435960278 creator A5045182250 @default.
- W2435960278 creator A5048265515 @default.
- W2435960278 creator A5066384937 @default.
- W2435960278 creator A5072142792 @default.
- W2435960278 creator A5080862333 @default.
- W2435960278 creator A5083342218 @default.
- W2435960278 creator A5089580045 @default.
- W2435960278 date "1996-01-01" @default.
- W2435960278 modified "2023-09-23" @default.
- W2435960278 title "[The action of tiazofurin on the development of sea urchin embryos and larvae]." @default.
- W2435960278 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8637672" @default.
- W2435960278 hasPublicationYear "1996" @default.
- W2435960278 type Work @default.
- W2435960278 sameAs 2435960278 @default.
- W2435960278 citedByCount "0" @default.
- W2435960278 crossrefType "journal-article" @default.
- W2435960278 hasAuthorship W2435960278A5013379343 @default.
- W2435960278 hasAuthorship W2435960278A5020843244 @default.
- W2435960278 hasAuthorship W2435960278A5035161884 @default.
- W2435960278 hasAuthorship W2435960278A5040493655 @default.
- W2435960278 hasAuthorship W2435960278A5045182250 @default.
- W2435960278 hasAuthorship W2435960278A5048265515 @default.
- W2435960278 hasAuthorship W2435960278A5066384937 @default.
- W2435960278 hasAuthorship W2435960278A5072142792 @default.
- W2435960278 hasAuthorship W2435960278A5080862333 @default.
- W2435960278 hasAuthorship W2435960278A5083342218 @default.
- W2435960278 hasAuthorship W2435960278A5089580045 @default.
- W2435960278 hasConcept C105702510 @default.
- W2435960278 hasConcept C118716 @default.
- W2435960278 hasConcept C129536746 @default.
- W2435960278 hasConcept C181199279 @default.
- W2435960278 hasConcept C196843134 @default.
- W2435960278 hasConcept C2776908312 @default.
- W2435960278 hasConcept C2779436081 @default.
- W2435960278 hasConcept C55493867 @default.
- W2435960278 hasConcept C6047887 @default.
- W2435960278 hasConcept C86803240 @default.
- W2435960278 hasConcept C87073359 @default.
- W2435960278 hasConcept C95444343 @default.
- W2435960278 hasConceptScore W2435960278C105702510 @default.
- W2435960278 hasConceptScore W2435960278C118716 @default.
- W2435960278 hasConceptScore W2435960278C129536746 @default.
- W2435960278 hasConceptScore W2435960278C181199279 @default.
- W2435960278 hasConceptScore W2435960278C196843134 @default.
- W2435960278 hasConceptScore W2435960278C2776908312 @default.
- W2435960278 hasConceptScore W2435960278C2779436081 @default.
- W2435960278 hasConceptScore W2435960278C55493867 @default.
- W2435960278 hasConceptScore W2435960278C6047887 @default.
- W2435960278 hasConceptScore W2435960278C86803240 @default.
- W2435960278 hasConceptScore W2435960278C87073359 @default.
- W2435960278 hasConceptScore W2435960278C95444343 @default.
- W2435960278 hasIssue "1" @default.
- W2435960278 hasLocation W24359602781 @default.
- W2435960278 hasOpenAccess W2435960278 @default.
- W2435960278 hasPrimaryLocation W24359602781 @default.
- W2435960278 hasRelatedWork W1988387529 @default.
- W2435960278 hasRelatedWork W2000195604 @default.
- W2435960278 hasRelatedWork W2026298450 @default.
- W2435960278 hasRelatedWork W2029582187 @default.
- W2435960278 hasRelatedWork W2038891440 @default.
- W2435960278 hasRelatedWork W2064127430 @default.
- W2435960278 hasRelatedWork W2091832220 @default.
- W2435960278 hasRelatedWork W2094344397 @default.
- W2435960278 hasRelatedWork W2240017123 @default.
- W2435960278 hasRelatedWork W2435960278 @default.
- W2435960278 hasVolume "27" @default.
- W2435960278 isParatext "false" @default.
- W2435960278 isRetracted "false" @default.
- W2435960278 magId "2435960278" @default.
- W2435960278 workType "article" @default.