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- W2436431878 abstract "Brain metastasis is of frequent occurrence in patients with cancer of the lung. To ascertain if brain metastasis is preventable, 34 lung cancer patients without brain metastasis were treated with 4 cycles of VM-26 plus CCNU at 4-week intervals. As a control for comparison, an equal number of lung cancer patients free of brain metastasis were treated with chemotherapy protocol which did not include VM-26 and CCNU. The patients were monitored by clinical symptoms, signs and CT or MRI scan and were followed up for 4-12 months. The results indicate that none of the VM-26 plus CCNU-treated patients developed brain metastasis while brain metastasis occurred in 7 (20.5%) of 34 control patients. The difference was statistically significant (P < 0.05)." @default.
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- W2436431878 date "1995-07-01" @default.
- W2436431878 modified "2023-09-23" @default.
- W2436431878 title "[VM-26 plus CCNU in the prevention of brain metastasis in lung cancer patients]." @default.
- W2436431878 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7587906" @default.
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