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- W2436729526 abstract "ABSTRACT The rat is a suitable model to study human rotator cuff pathology owing to the similarities in morphological anatomy structure. However, few studies have reported the composition muscle fiber types of rotator cuff muscles in the rat. In this study, the myosin heavy chain (MyHC) isoforms were stained by immunofluorescence to show the muscle fiber types composition and distribution in rotator cuff muscles of the rat. It was found that rotator cuff muscles in the rat were of mixed fiber type composition. The majority of rotator cuff fibers labeled positively for MyHCII. Moreover, the rat rotator cuff muscles contained hybrid fibers. So, compared with human rotator cuff muscles composed partly of slow‐twitch fibers, the majority of fast‐twitch fibers in rat rotator cuff muscles should be considered when the rat model study focus on the pathological process of rotator cuff muscles after injury. Gaining greater insight into muscle fiber types in rotator cuff muscles of the rat may contribute to elucidate the mechanism of pathological change in rotator cuff muscles‐related diseases. Anat Rec, 299:1397–1401, 2016. © 2016 Wiley Periodicals, Inc." @default.
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- W2436729526 date "2016-07-09" @default.
- W2436729526 modified "2023-10-16" @default.
- W2436729526 title "Composition of Muscle Fiber Types in Rat Rotator Cuff Muscles" @default.
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- W2436729526 doi "https://doi.org/10.1002/ar.23384" @default.
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