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- W243751111 abstract "The ability of the developing, nonprecocial newborn mammal to produce mature physiological and behavioral responses may in part depend upon the functional status of monoamine-containing neurons in the brain and periphery. Alterations produced in the patterns of locomotor activity, elective food consumption, and thermoregulation produced by various drugs thought to act via monoaminergic neurons, also change as a function of the age of the organism. Monoamine-containing neurons are not fully mature at birth in neonatal animals such as the rat: they are less able to synthesize, store, inactivate, release, and respond to neurotransmitters than are corresponding neurons in adult animals; moreover, not all of their synaptic connections have been made. The significance of changes in the developing monoamine neurons are discussed in relationship to their roles in determining the course of physiological and behavioral ontogenesis." @default.
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- W243751111 date "1974-01-01" @default.
- W243751111 modified "2023-09-25" @default.
- W243751111 title "BRAIN AND PERIPHERAL MONOAMINES: POSSIBLE ROLE IN THE ONTOGENESIS OF NORMAL AND DRUG-INDUCED RESPONSES IN THE IMMATURE MAMMAL" @default.
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- W243751111 doi "https://doi.org/10.1016/b978-0-08-017917-9.50050-0" @default.
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