Matches in SemOpenAlex for { <https://semopenalex.org/work/W2439407844> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2439407844 endingPage "22" @default.
- W2439407844 startingPage "418" @default.
- W2439407844 abstract "To study the relationship between 6A8 alpha-mannosidase expression and growth of CNE-2L2 cells, a human nasopharyngeal carcinoma cell line.Recombinant adeno-associated virus vector (rAAV) was used as a mediator to transfer an antisense or a sense fragment of 6A8 cDNA into CNE-2L2 cells. 6A8 alpha-mannosidase expression was detected by means of mAb 6A8a staining, alpha-mannosidase activity assay and ConA binding test. Cell growth was examined by means of MTT and colony formation. Tumor growth at the inoculated site of the cells in nude mice was detected after 8 weeks.Transduction of antisense 6A8 could reduce the expression of 6A8 alpha-mannosidase. In comparison to those in controls, the wild type, the mock-transduced and the sense 6A8-transduced cells, the MTT value, the colony number formed and the tumor weight grown at the inoculated site of cells were significantly decreased in the antisense 6A8-transduced cells (P < 0.001).Decreased expression of 6A8 alpha-mannosidase caused an inhibition of CNE-2L2 cell growth." @default.
- W2439407844 created "2016-06-24" @default.
- W2439407844 creator A5017686804 @default.
- W2439407844 creator A5029007816 @default.
- W2439407844 creator A5029112877 @default.
- W2439407844 creator A5037029521 @default.
- W2439407844 date "2001-10-01" @default.
- W2439407844 modified "2023-09-27" @default.
- W2439407844 title "[Growth inhibition of human nasopharyngeal carcinoma cell CNE-2L2 caused by suppression of 6A8 alpha-mannosidase expression]." @default.
- W2439407844 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12905853" @default.
- W2439407844 hasPublicationYear "2001" @default.
- W2439407844 type Work @default.
- W2439407844 sameAs 2439407844 @default.
- W2439407844 citedByCount "0" @default.
- W2439407844 crossrefType "journal-article" @default.
- W2439407844 hasAuthorship W2439407844A5017686804 @default.
- W2439407844 hasAuthorship W2439407844A5029007816 @default.
- W2439407844 hasAuthorship W2439407844A5029112877 @default.
- W2439407844 hasAuthorship W2439407844A5037029521 @default.
- W2439407844 hasConcept C126322002 @default.
- W2439407844 hasConcept C15152581 @default.
- W2439407844 hasConcept C153911025 @default.
- W2439407844 hasConcept C185592680 @default.
- W2439407844 hasConcept C2778997737 @default.
- W2439407844 hasConcept C2779707156 @default.
- W2439407844 hasConcept C2780783641 @default.
- W2439407844 hasConcept C509974204 @default.
- W2439407844 hasConcept C54355233 @default.
- W2439407844 hasConcept C55493867 @default.
- W2439407844 hasConcept C62112901 @default.
- W2439407844 hasConcept C71924100 @default.
- W2439407844 hasConcept C81885089 @default.
- W2439407844 hasConcept C86803240 @default.
- W2439407844 hasConceptScore W2439407844C126322002 @default.
- W2439407844 hasConceptScore W2439407844C15152581 @default.
- W2439407844 hasConceptScore W2439407844C153911025 @default.
- W2439407844 hasConceptScore W2439407844C185592680 @default.
- W2439407844 hasConceptScore W2439407844C2778997737 @default.
- W2439407844 hasConceptScore W2439407844C2779707156 @default.
- W2439407844 hasConceptScore W2439407844C2780783641 @default.
- W2439407844 hasConceptScore W2439407844C509974204 @default.
- W2439407844 hasConceptScore W2439407844C54355233 @default.
- W2439407844 hasConceptScore W2439407844C55493867 @default.
- W2439407844 hasConceptScore W2439407844C62112901 @default.
- W2439407844 hasConceptScore W2439407844C71924100 @default.
- W2439407844 hasConceptScore W2439407844C81885089 @default.
- W2439407844 hasConceptScore W2439407844C86803240 @default.
- W2439407844 hasIssue "5" @default.
- W2439407844 hasLocation W24394078441 @default.
- W2439407844 hasOpenAccess W2439407844 @default.
- W2439407844 hasPrimaryLocation W24394078441 @default.
- W2439407844 hasRelatedWork W1997659114 @default.
- W2439407844 hasRelatedWork W2357174515 @default.
- W2439407844 hasRelatedWork W2357329258 @default.
- W2439407844 hasRelatedWork W2366526533 @default.
- W2439407844 hasRelatedWork W2369428452 @default.
- W2439407844 hasRelatedWork W2389382321 @default.
- W2439407844 hasRelatedWork W2414813853 @default.
- W2439407844 hasRelatedWork W2441514375 @default.
- W2439407844 hasRelatedWork W2588942881 @default.
- W2439407844 hasRelatedWork W3140728205 @default.
- W2439407844 hasVolume "23" @default.
- W2439407844 isParatext "false" @default.
- W2439407844 isRetracted "false" @default.
- W2439407844 magId "2439407844" @default.
- W2439407844 workType "article" @default.